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[动物福利相关性以及实验动物处死的功能和形态学意义]

[Animal welfare relevance and the functional and morphological significance of the killing of laboratory animals].

作者信息

Messow C, Korn W D, Hackbarth H

出版信息

Dtsch Tierarztl Wochenschr. 1989 Apr;96(4):201-3.

PMID:2653779
Abstract

Euthanasia of experimental animals at the end of an experiment or when an experiment is terminated is relevant for two reasons: firstly, because of ethical reasons and of animal protection, secondly because of scientific evaluation of experimental results. Functional and morphologic alterations have up to now been inadequately observed and considered. Gradually varying different results depend on the different methods of euthanasia. Additionally single parameters of reactions in isolated organs vary depending on the method of euthanasia. These facts have not yet been respected in the discussion of so called alternate methods. The significance of functional and morphologic effects as seen in different methods of euthanasia is discussed with examples.

摘要

在实验结束时或实验终止时对实验动物实施安乐死有两个原因

其一,出于伦理和动物保护的考量;其二,出于对实验结果的科学评估。到目前为止,功能和形态学改变尚未得到充分观察和考量。不同的安乐死方法会逐渐产生不同的结果。此外,离体器官中反应的单个参数也会因安乐死方法的不同而有所变化。在关于所谓替代方法的讨论中,这些事实尚未得到重视。本文将通过实例探讨不同安乐死方法中所观察到的功能和形态学效应的意义。

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