Rao Angoori Gnaneshwar
Department of Dermatology, SVS Medical College, Mahbubnagar, Telangana, India.
Indian J Dermatol. 2015 Sep-Oct;60(5):524. doi: 10.4103/0019-5154.164448.
Coexistence of two different histopathological types of basal cell carcinomas (BCCs) in the same anatomical site is rare and interesting. Herein, we report a case of coexistence of nodular and adenoid BCC in a 78-year-old peasant who presented with a plaque and a globular swelling on left paranasal region of few years duration. Histopathology of skin biopsy with immunohistochemistry study using antibodies to S100, epithelial membrane antigen (EMA) and cytokeratin 7 (CK 7) from the margin of the ulcer and globular swelling confirmed the diagnosis that revealed features of nodular and adenoid basal cell carcinoma, respectively. Investigative work up did not reveal evidence of metastasis.
同一解剖部位存在两种不同组织病理学类型的基底细胞癌(BCC)十分罕见且有趣。在此,我们报告一例78岁农民,其左鼻旁区域出现一个斑块和一个球形肿物,持续数年,病理检查发现为结节型和腺样型基底细胞癌共存。对溃疡边缘和球形肿物进行皮肤活检,并使用抗S100、上皮膜抗原(EMA)和细胞角蛋白7(CK 7)抗体进行免疫组化研究,组织病理学检查确诊分别显示为结节型和腺样型基底细胞癌的特征。进一步检查未发现转移迹象。