Nordström U L, Patel N B, Taylor D J
Department of Obstetrics and Gynaecology, Ninewells Hospital and Medical School, Dundee, U.K.
Eur J Obstet Gynecol Reprod Biol. 1989 Mar;30(3):245-51. doi: 10.1016/0028-2243(89)90008-7.
Sixty-nine singleton high-risk pregnancies were assessed with both umbilical artery flow velocity waveform analysis and fetal biophysical profile within 10 days of delivery. An abnormal outcome, as defined as either small for gestational age at birth (SGA) or fetal distress during labour, was found in 30 babies. The peak systolic/end diastolic (A/B) ratio from the umbilical artery had a higher sensitivity (37%), specificity (92%), positive predictive value (79%) and negative predictive value (66%) than the fetal biophysical profile (27%, 82%, 53%, and 59%, respectively) in the diagnosis of abnormal outcome. Additional information from a real-time ultrasound assessment, such as the diagnosis of malformations and oligohydramnios could justify a combination of the two methods in antenatal monitoring of high-risk pregnancies.
69例单胎高危妊娠在分娩前10天内同时接受了脐动脉血流速度波形分析和胎儿生物物理评分评估。30例婴儿出现异常结局，定义为出生时小于胎龄（SGA）或分娩时胎儿窘迫。在异常结局的诊断中，脐动脉的收缩期峰值/舒张末期（A/B）比值比胎儿生物物理评分具有更高的敏感性（37%）、特异性（92%）、阳性预测值（79%）和阴性预测值（66%），胎儿生物物理评分的上述指标分别为27%、82%、53%和59%。实时超声评估的其他信息，如畸形诊断和羊水过少，可为两种方法联合用于高危妊娠的产前监测提供依据。
