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两种手术治疗强直性脊柱炎所致重度后凸畸形的比较:经椎弓根双椎体楔形截骨术与一期间断双节段经椎弓根楔形截骨术

Comparison of two surgeries in treatment of severe kyphotic deformity caused by ankylosing spondylitis: Transpedicular bivertebrae wedge osteotomy versus one-stage interrupted two-level transpedicular wedge osteotomy.

作者信息

Zhao Yongfei, Xu Hui, Zhang Yonggang, Wang Zheng, Zhang Xuesong, Wang Yan

机构信息

Department of Orthopedics, The General Hospital of Chinese People's Liberation Army (301 Hospital), 28 Fuxing Road, Beijing 100853, China.

Department of Orthopedics, Liaocheng People's Hospital, 67 Dongchang West Road, Liaocheng, Shandong Province 252004, China.

出版信息

Clin Neurol Neurosurg. 2015 Dec;139:252-7. doi: 10.1016/j.clineuro.2015.09.011. Epub 2015 Sep 25.

DOI:10.1016/j.clineuro.2015.09.011
PMID:26539670
Abstract

OBJECTIVE

To explore a simple and effective surgery for correcting severe kyphotic deformity caused by ankylosing spondylitis (AS).

MATERIALS AND METHODS

From January 2003 to December 2009, we respectively reviewed 32 patients with severe spinal kyphosis caused by AS with at least 2-year follow-up. Patients were divided into two groups, according to surgical methods: transpedicular bivertebrae wedge osteotomy (Group A) or one-stage interrupted two-level transpedicular wedge osteotomy (Group B). We recorded operating time and blood loss. Variation between pre- and post-operative sagittal imbalance, global spinal alignments (Cobb angle of T1 and L5, TLKA), lumbar lordosis, chin-brow vertical angle, thoracolumbar kyphosis angle in both groups were analyzed.

RESULTS

The average operating time was 236 ± 39 min and the average blood loss was 2200 ± 712 ml in Group A, and 252 ± 43 min, 2202 ± 737 ml respectively in Group B. There were no significant differences in operating time and blood loss. Variation between pre- and post-operative sagittal imbalance, global spinal alignments, lumbar lordosis and chin-brow vertical angle (CBVA) were comparable between the two groups. The variation of thoracolumbar kyphosis angle was significantly greater in Group B compared with Group A. SRS-22 scores were similar in the two groups at the 2-year follow-up and significantly improved compared with preoperative.

CONCLUSIONS

For correcting severe kyphosis in patients with AS, the one-stage interrupted two-level transpedicular wedge osteotomy is a safe and effective technique which can significantly improve the thoracolumbar kyphosis angle.

摘要

目的

探索一种简单有效的手术方法来矫正强直性脊柱炎(AS)所致的严重后凸畸形。

材料与方法

回顾2003年1月至2009年12月期间32例由AS导致严重脊柱后凸且至少随访2年的患者。根据手术方法将患者分为两组:经椎弓根双椎体楔形截骨术(A组)或一期间断两级经椎弓根楔形截骨术(B组)。记录手术时间和失血量。分析两组术前和术后矢状面失衡、整体脊柱排列(T1和L5的Cobb角、胸腰段后凸角)、腰椎前凸、眉垂距、胸腰段后凸角的变化。

结果

A组平均手术时间为236±39分钟,平均失血量为2200±712毫升;B组分别为252±43分钟、2202±737毫升。手术时间和失血量无显著差异。两组术前和术后矢状面失衡、整体脊柱排列、腰椎前凸和眉垂距的变化相当。与A组相比,B组胸腰段后凸角的变化明显更大。两组在2年随访时SRS - 22评分相似,且与术前相比均显著改善。

结论

对于矫正AS患者的严重后凸畸形,一期间断两级经椎弓根楔形截骨术是一种安全有效的技术,可显著改善胸腰段后凸角。

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