[天然免疫在耐受诱导中的作用]

[Role of innate immunity in tolerance induction].

作者信息

Dolgikh M S

机构信息

Shumakov Institute of Transplantology and Artificial organs.

出版信息

Biomed Khim. 2015 Sep-Oct;61(5):560-78. doi: 10.18097/PBMC20156105560.

DOI:10.18097/PBMC20156105560

PMID:26539864

Abstract

This review considers the role of innate immunity in mechanisms of transplant tolerance and rejection, analyse the role of innate immunity cells (dendritic cells-DC, NK, must and other cells) in these processes, and the pathes of creation of tolerogenic DC for transplant rejection therapy and tolerance.

摘要

本综述探讨了固有免疫在移植耐受和排斥机制中的作用，分析了固有免疫细胞（树突状细胞-DC、自然杀伤细胞-NK等细胞）在这些过程中的作用，以及为移植排斥治疗和耐受而产生耐受性DC的途径。