Carl-Ludwig-Institute for Physiology, Medical Faculty, University of Leipzig, Liebigstrasse 27, 04103 Leipzig, Germany.
Neuron. 2015 Nov 4;88(3):435-7. doi: 10.1016/j.neuron.2015.10.028.
To sustain ongoing synaptic transmission, new transmitter-filled vesicles must be recruited to empty release sites rapidly. However, in this issue of Neuron, Midorikawa and Sakaba (2015) show that, before being released, vesicles are tethered at the membrane for seconds.
为了维持持续的突触传递,必须迅速招募新的充满递质的囊泡来排空释放位点。然而,在本期《神经元》杂志上,Midorikawa 和 Sakaba(2015)的研究表明,在被释放之前,囊泡在数秒内被固定在细胞膜上。