Ferro Mark A, Van Lieshout Ryan J, Scott James G, Alati Rosa, Mamun Abdullah A, Dingle Kaeleen
a Department of Psychiatry & Behavioural Neurosciences .
b Department of Pediatrics , and .
J Asthma. 2016;53(3):282-8. doi: 10.3109/02770903.2015.1104694. Epub 2016 Jan 21.
This study examined associations of asthma and food allergy with symptoms of depression and anxiety at 14 and 21 years of age to determine whether condition-specific associations exist.
Data come from 4972 adolescents in the Mater University Study of Pregnancy. Symptoms of depression and anxiety were assessed using the Youth Self-Report and Young Adult Self-Report.
Condition-specific associations between asthma and depression, OR = 1.37 [1.12, 1.67] and between food allergy and anxiety, OR = 1.26 [1.04, 1.76] were found during adolescence, but not in young adulthood. Whereas asthma was associated with resolved depression, OR = 1.70 [1.13, 2.55], food allergy was associated with persistent anxiety, OR = 1.26 [1.01, 1.59].
In adolescents, asthma is associated with an increased risk of clinically relevant symptoms of depression and food allergy with an increased risk of clinically relevant symptoms of anxiety. Future research is needed to clarify directionality and mechanisms explaining these relationships. Health professionals should be aware of the increased risk of mental health problems in adolescents with asthma or food allergy.
本研究调查了14岁和21岁时哮喘及食物过敏与抑郁和焦虑症状之间的关联,以确定是否存在特定疾病的关联。
数据来自于莫特大学孕期研究中的4972名青少年。使用青少年自评量表和青年成人自评量表评估抑郁和焦虑症状。
在青少年期发现了哮喘与抑郁之间特定疾病的关联,比值比(OR)=1.37 [1.12, 1.67],以及食物过敏与焦虑之间的关联,OR = 1.26 [1.04, 1.76],但在青年期未发现。哮喘与缓解的抑郁相关,OR = 1.70 [1.13, 2.55],而食物过敏与持续性焦虑相关,OR = 1.26 [1.01, 1.59]。
在青少年中,哮喘与临床相关抑郁症状风险增加有关,食物过敏与临床相关焦虑症状风险增加有关。需要进一步的研究来阐明这些关系的方向性和机制。卫生专业人员应意识到哮喘或食物过敏青少年心理健康问题风险增加。