Fadlallah J, Rammaert B, Laurent S, Lanternier F, Pol S, Franck N, Mamzer M F, Dupin N, Lortholary O
Université Paris Descartes, Centre d'Infectiologie Necker Pasteur, IHU Imagine, Hôpital Necker Enfants Malades, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France.
Service d'anatomopathologie, Hôpital Cochin, Université Paris Descartes, APHP, Paris, France.
Transpl Infect Dis. 2016 Feb;18(1):105-11. doi: 10.1111/tid.12478. Epub 2016 Jan 30.
Mycobacterium avium-intracellulare complex (MAC) infections are well known in immunocompromised patients, notably in human immunodeficiency virus infection, but remain scarcely described in kidney transplantation. Moreover, cutaneous involvement in this infection is very unusual. We describe here a disseminated infection caused by MAC in a kidney transplant recipient revealed by cutaneous lesions. This case highlights the need for an exhaustive, iterative microbiologic workup in the context of an atypical disease presentation in a renal transplant patient, regardless of the degree of immunosuppression.
鸟分枝杆菌-胞内分枝杆菌复合体（MAC）感染在免疫功能低下的患者中很常见，尤其是在人类免疫缺陷病毒感染患者中，但在肾移植患者中仍鲜有报道。此外，这种感染累及皮肤的情况非常罕见。我们在此描述了一例肾移植受者因MAC感染播散并出现皮肤病变的病例。该病例强调，对于肾移植患者出现非典型疾病表现时，无论免疫抑制程度如何，都需要进行详尽、反复的微生物学检查。
