Cassat M, Wuerzner G, Burnier M
Rev Med Suisse. 2015 Sep 9;11(485):1648-54.
Shift work has become more and more common for the last thirty years. By definition, shift work disturbs the circadian rhythm and the internal clock. Even if the pathophysiological mechanisms are not well understood, a greater cardiovascular risk has been attributed to shift work. Cross-sectional and cohort studies have identified an association between shift work and an elevated blood pressure. Shift workers also present a higher incidence of hypertension and progression than day workers. Unfortunately, the heterogeneity of the studies, the multiple confounding factors, as well as the complexity to achieve a suitable comparison group make it impossible to draw firm clinical evidence. Nevertheless, this population needs a medical follow-up focused on the cardiovascular risks and blood pressure.
在过去三十年里,轮班工作变得越来越普遍。根据定义,轮班工作会扰乱昼夜节律和生物钟。即使病理生理机制尚未完全明确,但轮班工作已被认为会带来更大的心血管风险。横断面研究和队列研究已经证实轮班工作与血压升高之间存在关联。与日班工人相比,轮班工人患高血压的几率更高,病情进展也更快。不幸的是,研究的异质性、多种混杂因素以及难以设立合适的对照组使得难以得出确凿的临床证据。尽管如此,这一人群仍需要针对心血管风险和血压的医学随访。