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特发性非牵引性视网膜前膜患者接受观察的长期解剖学和功能结果

Long-term anatomical and functional results in patients undergoing observation for idiopathic nontractional epiretinal membrane.

作者信息

Rouvas Alexandros, Chatziralli Irini, Androu Aggeliki, Papakonstantinou Sotirios, Kouvari Maria S, Alonistiotis Dimitrios, Theodossiadis Panagiotis

机构信息

2 Department of Ophthalmology, Attikon University Hospital, Athens - Greece.

出版信息

Eur J Ophthalmol. 2016 May-Jun;26(3):273-8. doi: 10.5301/ejo.5000693. Epub 2015 Oct 21.

Abstract

PURPOSE

To evaluate the anatomical and functional course without surgical intervention in patients with nontractional epiretinal membrane (ERM) using spectral-domain optical coherence tomography (SD-OCT) in a long-term follow-up of 38.2 ± 30.6 months.

METHODS

Participants were 58 patients with nontractional ERM, which was defined as a tear or rip of the ERM in at least one line of OCT scan. All patients were observed without any surgical intervention. All patients underwent ophthalmologic examination, including best-corrected visual acuity (BCVA) measurement, funduscopy, and SD-OCT. Routine follow-up visits were performed every 6 months or earlier at the discretion of the investigator.

RESULTS

There was no statistically significant difference in BCVA or central foveal thickness (CFT) at all time points of the follow-up. About 84.4% of patients presented improvement or stabilization in BCVA at the end of the follow-up, while 53.4% of patients had a decrease in CFT. All patients had intact ellipsoid zone and none of them needed surgical intervention at the end of the follow-up of 38.2 ± 30.6 months.

CONCLUSIONS

In patients with nontractional ERM, BCVA and CFT may remain stable in a long-term follow-up. Therefore, if ellipsoid zone is intact and there is a tear or rip of ERM in at least one OCT scan, patients can be monitored and surgery may be deferred because of high percentage of structural and functional stability.

摘要

目的

使用光谱域光学相干断层扫描(SD-OCT)对非牵引性视网膜前膜(ERM)患者进行38.2±30.6个月的长期随访,以评估在无手术干预情况下的解剖和功能变化过程。

方法

研究对象为58例非牵引性ERM患者,定义为在至少一行OCT扫描中ERM有撕裂。所有患者均未接受任何手术干预而接受观察。所有患者均接受眼科检查,包括最佳矫正视力(BCVA)测量、眼底镜检查和SD-OCT。根据研究者的判断,每6个月或更早进行常规随访。

结果

随访各时间点的BCVA或中心凹厚度(CFT)均无统计学显著差异。随访结束时约84.4%的患者BCVA改善或稳定,而53.4%的患者CFT降低。所有患者的椭圆体带均完整,在38.2±30.6个月的随访结束时均无需手术干预。

结论

对于非牵引性ERM患者,BCVA和CFT在长期随访中可能保持稳定。因此,如果椭圆体带完整且至少在一次OCT扫描中有ERM撕裂,由于结构和功能稳定性比例较高,可对患者进行监测并推迟手术。

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