Rouvas Alexandros, Chatziralli Irini, Androu Aggeliki, Papakonstantinou Sotirios, Kouvari Maria S, Alonistiotis Dimitrios, Theodossiadis Panagiotis
2 Department of Ophthalmology, Attikon University Hospital, Athens - Greece.
Eur J Ophthalmol. 2016 May-Jun;26(3):273-8. doi: 10.5301/ejo.5000693. Epub 2015 Oct 21.
To evaluate the anatomical and functional course without surgical intervention in patients with nontractional epiretinal membrane (ERM) using spectral-domain optical coherence tomography (SD-OCT) in a long-term follow-up of 38.2 ± 30.6 months.
Participants were 58 patients with nontractional ERM, which was defined as a tear or rip of the ERM in at least one line of OCT scan. All patients were observed without any surgical intervention. All patients underwent ophthalmologic examination, including best-corrected visual acuity (BCVA) measurement, funduscopy, and SD-OCT. Routine follow-up visits were performed every 6 months or earlier at the discretion of the investigator.
There was no statistically significant difference in BCVA or central foveal thickness (CFT) at all time points of the follow-up. About 84.4% of patients presented improvement or stabilization in BCVA at the end of the follow-up, while 53.4% of patients had a decrease in CFT. All patients had intact ellipsoid zone and none of them needed surgical intervention at the end of the follow-up of 38.2 ± 30.6 months.
In patients with nontractional ERM, BCVA and CFT may remain stable in a long-term follow-up. Therefore, if ellipsoid zone is intact and there is a tear or rip of ERM in at least one OCT scan, patients can be monitored and surgery may be deferred because of high percentage of structural and functional stability.
使用光谱域光学相干断层扫描(SD-OCT)对非牵引性视网膜前膜(ERM)患者进行38.2±30.6个月的长期随访,以评估在无手术干预情况下的解剖和功能变化过程。
研究对象为58例非牵引性ERM患者,定义为在至少一行OCT扫描中ERM有撕裂。所有患者均未接受任何手术干预而接受观察。所有患者均接受眼科检查,包括最佳矫正视力(BCVA)测量、眼底镜检查和SD-OCT。根据研究者的判断,每6个月或更早进行常规随访。
随访各时间点的BCVA或中心凹厚度(CFT)均无统计学显著差异。随访结束时约84.4%的患者BCVA改善或稳定,而53.4%的患者CFT降低。所有患者的椭圆体带均完整,在38.2±30.6个月的随访结束时均无需手术干预。
对于非牵引性ERM患者,BCVA和CFT在长期随访中可能保持稳定。因此,如果椭圆体带完整且至少在一次OCT扫描中有ERM撕裂,由于结构和功能稳定性比例较高,可对患者进行监测并推迟手术。