Feldman R D, Schoenwald R, Kane J
Department of Internal Medicine, College of Medicine, University of Iowa, Iowa City 52242.
J Clin Pharmacol. 1989 Feb;29(2):158-61. doi: 10.1002/j.1552-4604.1989.tb03306.x.
The teaching of pharmacokinetics is acknowledged to be a key aspect of the core curriculum in clinical pharmacology and therapeutics, but is also widely acknowledged to be a very difficult part of the curriculum to teach. In order to assess the potential efficacy of interactive computer instruction in clinical pharmacokinetics we have developed a prototype computer-based instructional package. The courseware contains a comprehensive learning system including tutorial, simulation, and problem solving components. To determine the efficacy of this approach we randomly assigned senior medical student volunteers enrolled in the fourth year clinical pharmacology and therapeutics course to receive conventional teaching in clinical pharmacokinetics and/or adjuctive teaching using the computer-based instructional system. There was a high degree of acceptance of the program and over the short term of the trial those students using the computer program scored significantly higher [35%, P less than 0.05] on the mid-term pharmacokinetics quiz. The data suggests that a computerized instructional system in pharmacokinetics may significantly improve the teaching of clinical pharmacokinetics to medical students.
药代动力学教学被公认为是临床药理学与治疗学核心课程的关键部分，但也被广泛认为是课程中极难教授的内容。为了评估交互式计算机教学在临床药代动力学中的潜在效果，我们开发了一个基于计算机的教学原型软件包。该课件包含一个综合学习系统，包括辅导、模拟和问题解决组件。为了确定这种方法的效果，我们将参加四年级临床药理学与治疗学课程的高年级医学专业学生志愿者随机分组，让他们接受临床药代动力学的传统教学和/或使用基于计算机的教学系统进行辅助教学。该项目得到了高度认可，在试验的短期内，使用计算机程序的学生在中期药代动力学测验中的得分显著更高[提高了35%，P值小于0.05]。数据表明，药代动力学的计算机教学系统可能会显著改善对医学生的临床药代动力学教学。
