Westwood Heather, Eisler Ivan, Mandy William, Leppanen Jenni, Treasure Janet, Tchanturia Kate
Psychological Medicine, IoPPN, King's College London (KCL), PO59, London, SE5 8AF, UK.
Child and Adolescent Eating Disorders Service, Maudsley Hospital, London, SE5 8AZ, UK.
J Autism Dev Disord. 2016 Mar;46(3):964-77. doi: 10.1007/s10803-015-2641-0.
Interest in the link between Autism Spectrum Disorder (ASD) and Anorexia Nervosa (AN) has led to estimates of the prevalence of autistic traits in AN. This systematic review and meta-analysis assessed the use of the Autism-Spectrum Quotient (AQ) or abbreviated version (AQ-10) to examine whether patients with AN have elevated levels of autistic traits. Seven studies were identified and subsequent meta-analysis indicated that those with AN appear to have significant difficulties of a manner characteristic of ASD, relative to controls. Whilst this analysis supports previous indications of higher prevalence of ASD in AN, the aetiology of these traits remains unclear. Studies using more robust clinical measures of ASD within AN are needed to confirm what self-report measures appear to show.
对自闭症谱系障碍（ASD）与神经性厌食症（AN）之间联系的关注引发了对AN患者中自闭症特征患病率的估计。这项系统综述和荟萃分析评估了自闭症谱系商数（AQ）或缩写版（AQ-10）的使用情况，以研究AN患者的自闭症特征水平是否升高。共识别出7项研究，随后的荟萃分析表明，相对于对照组，AN患者似乎在ASD特有的方式上存在显著困难。虽然该分析支持了先前关于AN中ASD患病率较高的迹象，但这些特征的病因仍不清楚。需要在AN患者中使用更可靠的ASD临床测量方法进行研究，以证实自我报告测量方法似乎显示的结果。
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