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神经性厌食症与自闭症谱系障碍:系统综述。

Anorexia Nervosa and Autism Spectrum Disorder: A Systematic Review.

机构信息

Department of Psychology, Sigmund Freud University, Milan, Italy.

Department of Psychology, Sigmund Freud University, Milan, Italy; School of Applied Sciences, London South Bank University, London, U.K.

出版信息

Psychiatry Res. 2021 Dec;306:114271. doi: 10.1016/j.psychres.2021.114271. Epub 2021 Nov 10.

Abstract

BACKGROUND

Recent research has shown a growing interest in exploring the relationship between anorexia nervosa (AN) and autism spectrum disorder (ASD). Both conditions seem to share areas of cognitive, social and behavioural impairment, leading to relevant implications on treatment, especially when they are in comorbidity. This literature review aims to synthesise the latest studies on this topic to investigate the co-occurrence of AN and ASD, suggest future research directions and consider implications for treatment.

METHOD

Records were systematically (PRISMA guidelines) identified through PubMed, EBSCOhost, Scopus and Web of Science searching.

RESULTS

Thirteen studies met the eligibility criteria and were therefore included in the review. Results seem to confirm an overrepresentation of ASD symptoms in AN. Only few studies investigated the AN-ASD comorbidity in young people and report slightly lower rates than those conducted with adults.

CONCLUSIONS

Analysed studies suggest that while the comorbidity seems to exacerbate the severity of the condition, autistic traits appear to be rather stable over time and not related to body weight. Thus, future longitudinal studies and gender- specific assessment tools can help clarify the relationship between the two disorders, examine the onset of ASD symptoms and develop structured guidelines for treatment.

摘要

背景

最近的研究表明,人们越来越关注探索厌食症(AN)和自闭症谱系障碍(ASD)之间的关系。这两种情况似乎都存在认知、社交和行为障碍方面的问题,这对治疗有一定的影响,尤其是当它们同时存在时。本文献综述旨在综合最新研究,探讨 AN 和 ASD 的共病情况,提出未来的研究方向,并考虑对治疗的影响。

方法

根据 PRISMA 指南,通过 PubMed、EBSCOhost、Scopus 和 Web of Science 进行系统检索。

结果

符合入选标准的研究有 13 项,因此被纳入综述。结果似乎证实了 ASD 症状在 AN 中过度表现。只有少数研究调查了年轻人的 AN-ASD 共病情况,报告的发病率略低于针对成年人的研究。

结论

分析表明,虽然共病似乎会加重病情的严重程度,但自闭症特征似乎随时间相对稳定,与体重无关。因此,未来的纵向研究和性别特异性评估工具可以帮助阐明这两种疾病之间的关系,检查 ASD 症状的发生,并制定治疗的结构化指南。

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