Khadanga Sherrie, Lakoski Susan G, Hart Vicki, Sprague Brian L, Ba Yi, Hampton John M, Higgins Stephen T, Ades Philip A, Newcomb Polly A, Trentham-Dietz Amy
Department of Internal Medicine, University of Vermont, Burlington, Vermont.
Department of Internal Medicine, University of Vermont, Burlington, Vermont. Vermont Center on Behavior and Health and University of Vermont Cancer Center, Burlington, Vermont.
Cancer Epidemiol Biomarkers Prev. 2016 Jan;25(1):76-82. doi: 10.1158/1055-9965.EPI-15-0726. Epub 2015 Nov 6.
Change in health behaviors can occur among women newly diagnosed with ductal carcinoma in situ (DCIS). We sought to understand whether partnership status and socioeconomic status (SES) affected behavioral changes in body weight, physical activity, alcohol consumption, and smoking.
The Wisconsin In Situ Cohort (WISC) study comprises 1,382 women diagnosed with DCIS with information on demographics, SES factors, and pre- and post-DCIS diagnosis health-related behaviors. Logistic regression models were used to determine the association between partnership status, education, and income with change in behavior variables.
Higher educational attainment was associated with lower likelihood of stopping physical activity [OR, 0.45; 95% confidence interval (CI), 0.32-0.63; college vs. high school degree], or starting to drink alcohol (OR, 0.34; 95% CI, 0.15-0.80). Results suggested that higher family income was associated with lower likelihood of gaining >5% body mass index (P = 0.07) or stopping physical activity (P = 0.09). Living with a partner was not strongly associated with behavior changes.
Higher educational attainment and higher income, but not living with a partner, were associated with positive health behaviors after a DCIS diagnosis.
The associations between higher educational attainment and, to a lesser extent, higher income with positive health behaviors underscore the importance of considering SES when identifying those at risk for negative behavioral change after DCIS diagnosis.
新诊断为导管原位癌（DCIS）的女性可能会出现健康行为的改变。我们试图了解伴侣状况和社会经济地位（SES）是否会影响体重、身体活动、饮酒和吸烟等行为的变化。
威斯康星原位队列（WISC）研究纳入了1382名被诊断为DCIS的女性，这些女性提供了人口统计学、SES因素以及DCIS诊断前后与健康相关行为的信息。采用逻辑回归模型来确定伴侣状况、教育程度和收入与行为变量变化之间的关联。
较高的教育程度与停止身体活动的可能性较低相关[比值比（OR），0.45；95%置信区间（CI），0.32 - 0.63；大学学历与高中学历相比]，或开始饮酒的可能性较低相关（OR，0.34；95%CI，0.15 - 0.80）。结果表明，较高的家庭收入与体重指数增加>5%（P = 0.07）或停止身体活动（P = 0.09）的可能性较低相关。与伴侣同住与行为变化没有强烈关联。
较高的教育程度和较高的收入，但不包括与伴侣同住，与DCIS诊断后的积极健康行为相关。
较高的教育程度以及在较小程度上较高的收入与积极健康行为之间的关联强调了在确定DCIS诊断后有负面行为变化风险的人群时考虑SES的重要性。
