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关于肉类摄入与预防肌肉减少症的新见解:充分摄入肉类的所有理由

NOVEL INSIGHTS ON INTAKE OF MEAT AND PREVENTION OF SARCOPENIA: ALL REASONS FOR AN ADEQUATE CONSUMPTION.

作者信息

Rondanelli Mariangela, Perna Simone, Faliva Milena Anna, Peroni Gabriella, Infantino Vittoria, Pozzi Raffaella

机构信息

University of Pavia, Department of Public Health, Experimental and Forensic Medicine, Section of Human Nutrition, Endocrinology and Nutrition Unit, Azienda di Servizi alla Persona, Pavia, Italy..

出版信息

Nutr Hosp. 2015 Nov 1;32(5):2136-43. doi: 10.3305/nh.2015.32.5.9638.

Abstract

INTRODUCION

sarcopenia is defined as a syndrome characterized by progressive and generalized loss of muscle mass and strength. The main cause of sarcopenia is the alteration of protein metabolism, in which the proteolytic processes are not accompanied by an appropriate protein synthesis and muscle cells lose progressively the sensitivity to the anabolic stimulus. The most rational approach to delay the progression of sarcopenia and counteract the anabolic resistance is proper nutrition. Meat contains biologically active compounds, such as creatine, carnitine, Conjugated Linoleic Acid (CLA) which have significant impacts upon human protein metabolism.

METHODS

we performed a narrative literature review to evaluate the till-now evidence regarding: 1. adequate intake of meat in elderly as a topic for prevention of sarcopenia; 2. the correct intake of biologically active compounds contain in meat, which have significant impacts upon human protein metabolism and so have beneficial effects on prevention of sarcopenia. This review included 62 eligible studies.

RESULTS

the results demonstrated that in elderly the optimum diet therapy for the sarcopenia prevention and treatment, which must aim at achieving specific metabolic goals, must recommend the consumption of 113 g of meat (220 kcal; 30 g protein) five time a week.

CONCLUSION

in a varied and balanced diet, for preventing sarcopenia, it is recommended to assume meat 4-5 times a week (white meat 2 times per week, lean red meat less than 2 times per week, processed meat less than 1 time per week), as suggested in the diet pyramid for elderly.

摘要

引言

肌肉减少症被定义为一种以肌肉质量和力量进行性全身性丧失为特征的综合征。肌肉减少症的主要原因是蛋白质代谢的改变,其中蛋白水解过程没有伴随着适当的蛋白质合成,肌肉细胞逐渐失去对合成代谢刺激的敏感性。延缓肌肉减少症进展并对抗合成代谢抵抗的最合理方法是适当的营养。肉类含有生物活性化合物,如肌酸、肉碱、共轭亚油酸(CLA),它们对人体蛋白质代谢有重大影响。

方法

我们进行了一项叙述性文献综述,以评估迄今为止关于以下方面的证据:1. 老年人摄入足够的肉类作为预防肌肉减少症的一个话题;2. 正确摄入肉类中含有的对人体蛋白质代谢有重大影响从而对预防肌肉减少症有有益作用的生物活性化合物。该综述纳入了62项符合条件的研究。

结果

结果表明,对于老年人预防和治疗肌肉减少症的最佳饮食疗法,必须旨在实现特定的代谢目标,应建议每周食用113克肉类(220千卡;30克蛋白质),分五次食用。

结论

在多样化和均衡的饮食中,为预防肌肉减少症,建议如老年人饮食金字塔中所建议的那样,每周食用肉类4 - 5次(每周食用白肉2次,瘦红肉少于2次,加工肉类少于1次)。

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