Rosety Miguel Angel, Pery Maria Teresa, Rodriguez-Pareja Maria Antonia, Diaz Antonio, Rosety Jesus, Garcia Natalia, Brenes-Martin Francisco, Rosety-Rodríguez Manuel, Toro Rocío, Ordoñez Francisco Javier, Rosety Ignacio
University of Cadiz, Spain..
University of Cadiz. Hospital "Puerta del Mar", Spain..
Nutr Hosp. 2015 Nov 1;32(5):2193-7. doi: 10.3305/nh.2015.32.5.9696.
this study was conducted to ascertain the effects of resistance circuit training on epicardial adipose tissue (EAT) in obese aged women. A secondary objective was to assess muscle damage induced by supervised resistance training to confirm the intervention program was effective and safe.
in the present interventional study, a total of 48 obese aged women were recruited from the community. Twenty-four of them were randomly assigned to perform a 12-week resistance circuit training programme, 3-days per week. This training was circularly performed in 6 stations: arm curl, leg extension, seated row, leg curl, triceps extension and leg press. The Jamar handgrip electronic dynamometer was used to assess maximal handgrip strength of the dominant hand. Two experienced observers assessed EAT by transthoracic two-dimensional echocardiography. Lastly, serum samples were analysed using one-step sandwich assays for creatine kinase activity (CK) and myoglobin (MB) concentration.
as was hypothesized, resistance training significantly reduced EAT thickness (8.4 ± 1.0 vs. 7.3 ± 1.3 mm; p = 0.014; d = 0.76) in the experimental group. Resistance training induced no significant changes in markers of muscle damage such as CK (181.6 ± 36.9 vs. 194.2 ± 37.8 U/l; p = 0.31) and MB (62.4 ± 7.1 vs. 67.3 ± 7.7 ng/ml; p = 0.26). No significant changes in any of the tested outcomes were found in the control group.
resistance training reduced EAT in aged obese women. A secondary finding was that the training program was effective and safe. While current results are promising, future studies are still required to consolidate this approach in clinical application.
本研究旨在确定抗阻循环训练对肥胖老年女性心外膜脂肪组织（EAT）的影响。第二个目标是评估监督性抗阻训练引起的肌肉损伤，以确认干预方案是有效且安全的。
在本干预性研究中，从社区招募了总共48名肥胖老年女性。其中24人被随机分配，每周进行3天、为期12周的抗阻循环训练计划。该训练在6个站点循环进行：弯臂举、腿伸展、坐姿划船、腿弯举、肱三头肌伸展和腿部推举。使用Jamar握力电子测力计评估优势手的最大握力。两名经验丰富的观察者通过经胸二维超声心动图评估EAT。最后，使用一步夹心分析法分析血清样本中的肌酸激酶活性（CK）和肌红蛋白（MB）浓度。
如假设的那样，抗阻训练显著降低了实验组的EAT厚度（8.4±1.0 vs. 7.3±1.3毫米；p = 0.014；d = 0.76）。抗阻训练未引起肌肉损伤标志物如CK（181.6±36.9 vs. 194.2±37.8 U/L；p = 0.31）和MB（62.4±7.1 vs. 67.3±7.7 ng/ml；p = 0.26）的显著变化。对照组中任何测试结果均未发现显著变化。
抗阻训练减少了老年肥胖女性的EAT。第二个发现是该训练方案有效且安全。虽然目前的结果很有前景，但仍需要未来的研究来巩固这种方法在临床应用中的地位。
