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[变应性支气管哮喘:支气管活检免疫荧光技术的评估]

[Allergic bronchial asthma: an evaluation of immunofluorescence technics on bronchial biopsies].

作者信息

Mantellini E, Salio M, Cremonte L G

机构信息

II Divisione Pneumologica, Ospedale Civile, Alessandria.

出版信息

Minerva Med. 1989 Mar;80(3):265-7.

PMID:2654761
Abstract

Although the immunofluorescence technique has mostly been applied to renal diseases, it may be of use in the examination of lung tissue. Immunofluorescence tests on bronchial bioptic samples can show: 1) presence of IgE, IgA, IgM, IgG and complement factors; 2) their location on the bronchial mucosa; 3) their relationships with epithelioid cells, mast cells and plasma cells. Patients with atopic asthma were examined. Bioptic samples were taken from the main bronchi and treated by immunofluorescence. Cellular positivity was found for IgE, IgA, IgM and complement components.

摘要

尽管免疫荧光技术大多应用于肾脏疾病,但它可能在肺组织检查中有用。对支气管活检样本进行的免疫荧光检测可以显示:1)IgE、IgA、IgM、IgG和补体因子的存在;2)它们在支气管黏膜上的位置;3)它们与上皮样细胞、肥大细胞和浆细胞的关系。对特应性哮喘患者进行了检查。从主支气管采集活检样本并进行免疫荧光处理。发现IgE、IgA、IgM和补体成分呈细胞阳性。

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