Nutr Rev. 1989 May;47(5):157-9. doi: 10.1111/j.1753-4887.1989.tb02824.x.
Biotin deficiency in chicks changed the leg-bone modeling pattern. The mid-diaphyseal cortex was thickest medially instead of laterally as in normal chicks. Furthermore, periosteal bone appositional and bone formation rates were reduced in tibiotarsi of biotin-deficient chicks.
雏鸡生物素缺乏改变了腿骨的塑形模式。与正常雏鸡不同，中骨干皮质最厚的部位在中部内侧而非外侧。此外，生物素缺乏雏鸡的胫跗骨骨膜骨沉积和骨形成速率降低。
