Raddaoui Emad, Almadi Majid A, Aljebreen Abdulrahman M, Alsaif Faisal
Division of Pathology, King Khalid University Hospital, King Saud University, Riyadh; Division of Pathology, Alfaisal University, Riyadh, Saudi Arabia.
Indian J Pathol Microbiol. 2015 Oct-Dec;58(4):448-52. doi: 10.4103/0377-4929.168868.
Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) sampling has become standard practice for the diagnosis of submucosal gastrointestinal (GI) lesions. The aim of this study was to determine the utility of EUS-guided FNA cytology in the diagnosis of deeply seated gastric mass lesions.
Thirteen patients with deeply seated gastric mass lesions were diagnosed by EUS-FNA. Adequate cytology material was present in all cases. Cell blocks were available in 10 cases. Surgical resections were performed in 8 cases. Immunohistochemical (IHC) studies were done on cell blocks in 9 cases and on 6 resected specimens. Seven cases has proved to be GI stromal tumors (GIST), in four of them, cell blocks were available, and resection for GIST was performed in 5 cases. IHC stains that were performed in cytology, as well as resection specimens, revealed similar results in each patient.
EUS-FNA cytology, when combined with a histologic assessment of cell blocks provides accurate and efficient tissue diagnosis of a wide variety of deeply seated gastric mass lesions.
内镜超声引导下细针穿刺抽吸（EUS-FNA）采样已成为诊断胃肠道（GI）黏膜下病变的标准操作。本研究的目的是确定EUS引导下FNA细胞学检查在诊断深部胃肿物病变中的效用。
13例深部胃肿物病变患者通过EUS-FNA进行诊断。所有病例均有足够的细胞学材料。10例有细胞块。8例进行了手术切除。9例对细胞块进行了免疫组织化学（IHC）研究，6例对切除标本进行了研究。7例被证实为胃肠道间质瘤（GIST），其中4例有细胞块，5例进行了GIST切除。在细胞学以及切除标本中进行的IHC染色在每位患者中显示出相似的结果。
EUS-FNA细胞学检查与细胞块的组织学评估相结合，可为多种深部胃肿物病变提供准确、有效的组织诊断。
