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睾丸内伴有小畸胎瘤灶的子宫内膜样卵黄囊瘤:一例报告并文献复习

Endometrioid like yolk sac tumor of the testis with small teratomatous foci: A case report and review of the literature.

作者信息

Hazarika Prabir

机构信息

Department of Pathology, Silchar Medical College and Hospital, Silchar, Assam, India.

出版信息

Indian J Pathol Microbiol. 2015 Oct-Dec;58(4):557-9. doi: 10.4103/0377-4929.168869.

DOI:10.4103/0377-4929.168869
PMID:26549093
Abstract

I have reported a case of endometrioid like yolk sac tumor of the testis in a 20-year-old boy. Endometrioid like yolk sac tumor is a rare tumor. A few cases have been reported in ovary. In case of male, a case of pure glandular endometrioid like yolk sac tumor is reported in a 43 years male in right undescended testis and another case of abdominal metastasis showing endometrioid pattern from mixed testicular germ cell tumor comprising of teratoma and embryonal carcinoma. My patient was a 20-year-old male presented with painless enlargement of right testis. Grossly the tumor was glistening creamish white with a multicystic appearance. Histopathological examination showed the tumor to be composed of glandular elements resembling early secretory endometrium, foci of keratinized thin squamous epithelium and a single focus of benign cartilage. The glandular elements show immunohistochemical positivity for AFP, cytokeratin 7 (CK7) and epithelial membrane antigen (EMA).

摘要

我报告了一例20岁男孩睾丸的子宫内膜样卵黄囊瘤。子宫内膜样卵黄囊瘤是一种罕见的肿瘤。卵巢中曾有少数病例报道。在男性中,有一例43岁男性右侧隐睾的纯腺性子宫内膜样卵黄囊瘤,另一例是腹部转移灶,显示来自由畸胎瘤和胚胎癌组成的混合性睾丸生殖细胞肿瘤的子宫内膜样形态。我的患者是一名20岁男性,表现为右侧睾丸无痛性肿大。大体上,肿瘤呈闪亮的灰白色,外观为多囊性。组织病理学检查显示肿瘤由类似早期分泌期子宫内膜的腺性成分、角化薄鳞状上皮灶和单个良性软骨灶组成。腺性成分对甲胎蛋白、细胞角蛋白7(CK7)和上皮膜抗原(EMA)呈免疫组化阳性。

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