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慢性神经源性下尿路功能障碍患者的膀胱管理

Bladder management in individuals with chronic neurogenic lower urinary tract dysfunction.

作者信息

Krebs J, Wöllner J, Pannek J

机构信息

Clinical Trial Unit, Swiss Paraplegic Centre, Nottwil, Switzerland.

NeuroUrology, Swiss Paraplegic Centre, Nottwil, Switzerland.

出版信息

Spinal Cord. 2016 Aug;54(8):609-13. doi: 10.1038/sc.2015.196. Epub 2015 Nov 10.

Abstract

STUDY DESIGN

Retrospective investigation.

OBJECTIVES

To investigate the association of patient and injury characteristics with bladder evacuation by indwelling catheterization in patients with chronic neurogenic lower urinary tract dysfunction (NLUTD).

SETTING

Tertiary urologic referral center.

METHODS

The patient database was screened for patients with chronic (>12 months) NLUTD. Patient characteristics and bladder management details were collected. Binary logistic regression analysis was used to investigate the effects of the investigated factors on bladder evacuation by indwelling catheterization.

RESULTS

The data of 1263 patients with a median age of 47 years (range 11-89 years) and a median NLTUD duration of 15.2 years (range 1.0-63.4 years) were investigated. The most common bladder evacuation method was intermittent catheterization (IC; 41.3%) followed by triggered reflex voiding (25.7%), suprapubic catheterization (11.8%), sacral anterior root stimulation (7.3%), spontaneous voiding (7.0%), abdominal straining (5.7%) and transurethral catheterization (1.3%). Female gender, tetraplegia, an age older than 45 years and injury duration were significant (<0.001) predictors of indwelling catheterization. The odds of bladder evacuation by indwelling catheterization were increased ~2.5, 3 and 4 times in women, patients older than 45 years and tetraplegics, respectively.

CONCLUSIONS

IC is the most common bladder evacuation method. However, the majority of individuals with NLUTD are using other evacuation methods, because factors such as functional deficiencies, mental impairment or the social situation are relevant for choosing a bladder evacuation method. Individuals at risk of indwelling catheterization can be identified based on female gender, age, injury severity and injury duration.

摘要

研究设计

回顾性调查。

目的

探讨慢性神经源性下尿路功能障碍(NLUTD)患者的患者及损伤特征与留置导尿膀胱排空之间的关联。

地点

三级泌尿外科转诊中心。

方法

在患者数据库中筛查慢性(>12个月)NLUTD患者。收集患者特征和膀胱管理细节。采用二元逻辑回归分析研究调查因素对留置导尿膀胱排空的影响。

结果

对1263例患者的数据进行了调查,这些患者的中位年龄为47岁(范围11 - 89岁),NLUTD中位病程为15.2年(范围1.0 - 63.4年)。最常见的膀胱排空方法是间歇性导尿(IC;41.3%),其次是触发反射性排尿(25.7%)、耻骨上膀胱造瘘(11.8%)、骶前根刺激(7.3%)、自主排尿(7.0%)、腹部加压排尿(5.7%)和经尿道导尿(1.3%)。女性、四肢瘫痪、年龄大于45岁和损伤病程是留置导尿的显著(<0.001)预测因素。女性、年龄大于45岁的患者和四肢瘫痪患者通过留置导尿进行膀胱排空的几率分别增加约2.5倍、3倍和4倍。

结论

IC是最常见的膀胱排空方法。然而,大多数NLUTD患者使用其他排空方法,因为功能缺陷、精神障碍或社会状况等因素与膀胱排空方法的选择相关。可根据性别、年龄、损伤严重程度和损伤病程识别有留置导尿风险的个体。

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