循环祖细胞与儿童心血管疾病
Circulating Progenitor Cells and Childhood Cardiovascular Disease.
作者信息
Kort Eric J, Croskey Lacey, Scibienski Taryn, Rajasekaran Surender, Jovinge Stefan
机构信息
DeVos Cardiovascular Research Program of Spectrum Health and Van Andel Research Institute, 100 Michigan Street NE, Grand Rapids, MI, 49503, USA.
Michigan State University, College of Human Medicine, 15 Michigan Street NE, Grand Rapids, MI, USA.
出版信息
Pediatr Cardiol. 2016 Feb;37(2):225-31. doi: 10.1007/s00246-015-1300-8. Epub 2015 Nov 11.
Circulating progenitor cells have been extensively studied in the context of heart disease in adults. In these patients, they have been demonstrated to be markers of myocardial injury and recovery as well as potential therapeutic agents. However, studies in children are much more limited. Here we review current knowledge pertaining to circulating progenitor cells in the context of childhood cardiovascular disease. Priorities for further research are also highlighted.
循环祖细胞在成人心血管疾病的背景下已得到广泛研究。在这些患者中，它们已被证明是心肌损伤和恢复的标志物以及潜在的治疗剂。然而，关于儿童的研究则要有限得多。在此，我们综述了儿童心血管疾病背景下有关循环祖细胞的现有知识。同时也强调了进一步研究的重点。
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