Gomez-Gomez Enrique, Malde Sachin, Spilotros Marco, Shah P J, J Greenwell Tamsin, Ockrim Jeremy L
a Department of Urology , University College London Hospital , London , UK.
b Department of Urology , Reina Sofia University Hospital, IMIBIC , Cordoba , Spain.
Scand J Urol. 2016 Jun;50(3):192-9. doi: 10.3109/21681805.2015.1106579. Epub 2015 Nov 10.
Complex ureteric stricture disease in contemporary practice is typically related to prior pelvic surgery, radiotherapy, or complicated, repeated retrograde stone surgery, although outcomes in this group have not been well studied. The aim of this study was to report medium-term outcomes with ileal-ureter substitution for complex ureteric stricture disease.
All patients who had undergone ureteric reconstructive surgery using small bowel over a 5 year period between 2010 and 2015 were identified from the theatre database and their case notes reviewed. Data were collected on aetiology of ureteric stricture, prior surgery or radiotherapy, baseline renal function and comorbidity. Postoperative complications were recorded using the Clavien-Dindo classification, and overall outcome and need for further intervention were documented.
Nine patients underwent ileal-ureter substitution for complex ureteric stricture disease over this period, with four having bilateral ileal interpositions. Median age was 48 years (38-62 years) with a median follow-up of 17 months (1-40 months). Simple untailored ileal segments and refluxing anastomoses were used in all cases. One case of anastomotic leak and restricture required reintervention, but all others had favourable outcomes with no stricture and no requirement for further intervention. Two patients reported recurrent cystitis following surgery but there was no deterioration in renal function in any patient, with no metabolic complications reported.
Ileal-ureter substitution surgery is a valuable option for selected patients with complex, difficult-to-treat ureteric defects that cannot be bridged by other methods. Simple onlay techniques do not seem to affect renal or metabolic function. Avoiding the extra complexity of tailored and tunnelled anastomoses may reduce the potential morbidity and reintervention rate in patients with challenging surgical fields.
在当代医疗实践中,复杂性输尿管狭窄疾病通常与既往盆腔手术、放疗或复杂的反复逆行结石手术有关,尽管该群体的治疗结果尚未得到充分研究。本研究的目的是报告采用回肠代输尿管术治疗复杂性输尿管狭窄疾病的中期结果。
从手术数据库中识别出2010年至2015年期间接受小肠输尿管重建手术的所有患者,并查阅其病历。收集输尿管狭窄的病因、既往手术或放疗、基线肾功能和合并症等数据。使用Clavien-Dindo分类法记录术后并发症,并记录总体结果和进一步干预的需求。
在此期间,9例患者接受了回肠代输尿管术治疗复杂性输尿管狭窄疾病,其中4例为双侧回肠置入。中位年龄为48岁(38 - 62岁),中位随访时间为17个月(1 - 40个月)。所有病例均采用简单的非定制回肠段和抗反流吻合术。1例吻合口漏和狭窄需要再次干预,但其他所有患者均取得良好结果,无狭窄且无需进一步干预。2例患者术后报告复发性膀胱炎,但所有患者肾功能均无恶化,未报告代谢并发症。
对于某些患有复杂、难以治疗且无法通过其他方法解决的输尿管缺损的患者,回肠代输尿管术是一种有价值的选择。简单的覆盖技术似乎不会影响肾脏或代谢功能。避免定制和隧道式吻合的额外复杂性可能会降低手术视野具有挑战性的患者的潜在发病率和再次干预率。