Xu Yue-Min, Feng Chao, Kato Haruaki, Xie Hong, Zhang Xin-Ru
Department of Urology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai, China.
Department of Urology, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai, China.
Urology. 2016 Feb;88:201-6. doi: 10.1016/j.urology.2015.11.005. Epub 2015 Nov 11.
To investigate the long-term outcome of ileal ureteric replacement using a proximal antirefluxing technique for the treatment of long-segment ureteric strictures.
Between January 1997 and December 2013, 41 patients with a long ureteral stricture or defect and 3 patients with unilateral mid-lower ureteral cancer (20 bilateral and 24 unilateral, 28 males and 16 females) were treated by ureteral substitution using a proximal antirefluxing technique. The distal part of the upper ureter (4 cm) was fixed between the psoas muscle and the ileal segment (the iliopsoas tunnel technique). The distal ileum was connected to the urinary bladder with an end-to-side anastomosis. A successful outcome was defined as the absence of major complications, worsening baseline renal function, metabolic derangements, or obstruction.
One patient with unilateral mid-lower ureteral cancer died 3 years postoperatively because of metastasis, and the remaining 43 patients were followed for 12-180 months (mean 69 months). Intravenous urography showed that the hydronephrosis improved significantly or disappeared after 6-12 months in 34 patients, with improvement in 9 patients. Cystography showed no evidence of ileoureteral reflux. Seven patients needed long-term oral alkalization to prevent hyperchloremic acidosis.
In our experience, outcomes following subtotal ureteric replacement are encouraging. The ileal ureter replacement by the proximal antirefluxing technique appears to be a reliable procedure for treating long-segment ureteral stricture and preservation of renal function.
探讨采用近端抗反流技术行回肠代输尿管术治疗长段输尿管狭窄的远期疗效。
1997年1月至2013年12月,41例长段输尿管狭窄或缺损患者及3例单侧输尿管中下段癌患者(双侧20例,单侧24例;男性28例,女性16例)接受了采用近端抗反流技术的输尿管替代术。输尿管上段远端(4 cm)固定于腰大肌与回肠段之间(髂腰隧道技术)。回肠远端与膀胱行端侧吻合。成功的结果定义为无严重并发症、基线肾功能恶化、代谢紊乱或梗阻。
1例单侧输尿管中下段癌患者术后3年因转移死亡,其余43例患者随访12 - 180个月(平均69个月)。静脉肾盂造影显示,34例患者在6 - 12个月后肾积水明显改善或消失,9例患者有所改善。膀胱造影未显示回肠输尿管反流。7例患者需要长期口服碱化药物以预防高氯性酸中毒。
根据我们的经验,输尿管大部替代术后的疗效令人鼓舞。采用近端抗反流技术行回肠代输尿管术似乎是治疗长段输尿管狭窄及保留肾功能的可靠方法。