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颅内蛛网膜囊肿患儿:分类与治疗

Children With Intracranial Arachnoid Cysts: Classification and Treatment.

作者信息

Tan Zhen, Li Yongxin, Zhu Fengjun, Zang Dongdong, Zhao Cailei, Li Cong, Tong Dan, Zhang Heye, Chen Qian

机构信息

From the Department of Pediatric Neurosurgery, ShenZhen Children Hospital, ShenZhen (ZT, FZ, DZ, CL, DT, QC); Institute of Anatomy, Southern Medical University, GuangZhou (YL); Department of Pediatric Radiology, ShenZhen Children Hospital (CZ); and Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China (HZ).

出版信息

Medicine (Baltimore). 2015 Nov;94(44):e1749. doi: 10.1097/MD.0000000000001749.

Abstract

We performed a dynamic study of arachnoid cysts (ACs) using magnetic resonance cisternography (MRC) and proposed a classification of ACs.Twenty-three suitable patients in our hospital entered into this study according to our inclusion criteria. MRC images were collected in all the subjects at 1 and 24 hours after the administration of intrathecal gadolinium-diethylenetriamine penta-acetic acid (Gd-DTPA). We allocate the enrolled patients into 2 groups, MRC group and surgery group. The MRC results were considered before treatment in 1 group (MRC group, 13 patients), whereas another group was surgically treated without considering the MRC results (surgery group, 10 patients). We calculated the enhanced area of cyst using modified MacDonald Criteria from the images and measured the surrounding subarachnoid area as the reference.We found that it was practically useful to quantify 3 types of ACs, complete communicating, incomplete communicating, and noncommunicating, according to MRC results in this study. All the subjects in both groups are closely observed before the treatment and the follow-up using the MRI examination. In the surgery group, 5 patients were found that the area of cysts shrank in the follow-up stage. However, there was no significant difference in the percentage shrinkage area between the 2 groups.We concluded that MRC with Gd-DTPA as a contrast agent is of significant clinical value for the diagnosis and treatment of children with intracranial ACs. This classification based on dynamic MRC is useful for making surgical recommendations.

摘要

我们使用磁共振脑池造影(MRC)对蛛网膜囊肿(ACs)进行了动态研究,并提出了ACs的分类方法。根据纳入标准,我院23例合适的患者进入本研究。所有受试者在鞘内注射钆喷酸葡胺(Gd-DTPA)后1小时和24小时采集MRC图像。我们将入选患者分为两组,MRC组和手术组。一组(MRC组,13例患者)在治疗前考虑MRC结果,而另一组(手术组,10例患者)在不考虑MRC结果的情况下接受手术治疗。我们根据图像使用改良的MacDonald标准计算囊肿的强化面积,并测量周围蛛网膜下腔面积作为参考。我们发现在本研究中,根据MRC结果对完全交通性、不完全交通性和非交通性3种类型的ACs进行量化实际上是有用的。两组所有受试者在治疗前和随访期间均使用MRI检查进行密切观察。在手术组中,5例患者在随访阶段发现囊肿面积缩小。然而,两组之间的缩小面积百分比没有显著差异。我们得出结论,以Gd-DTPA作为造影剂的MRC对颅内ACs患儿的诊断和治疗具有重要临床价值。这种基于动态MRC的分类方法有助于提出手术建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7231/4915874/e8f1aac71e67/medi-94-e1749-g002.jpg

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