朗格汉斯细胞组织细胞增多症与霍奇金淋巴瘤伴发的淋巴结受累

Concomitant nodal involvement by Langerhans cell histiocytosis and Hodgkin's lymphoma.

作者信息

Geurten Claire, Thiry Albert, Jamblin Paul, Demarche Martine, Hoyoux Claire

机构信息

Faculty of Medicine, University of Liege.

Department of Anatomopathology, Clinique CHR de la Citadelle, Liège, Belgium.

出版信息

Pediatr Int. 2015 Dec;57(6):1214-7. doi: 10.1111/ped.12724. Epub 2015 Nov 10.

DOI:10.1111/ped.12724

PMID:26556799

Abstract

A 10-year-old girl with a family history of Hodgkin's lymphoma presented with a 2 month history of cervical lymphadenopathy and weight loss. Biopsy indicated concomitant nodal involvement by Langerhans cell histiocytosis and Hodgkin's lymphoma. Such an association is rare, especially so in children, but is not an isolated phenomenon, thereby prompting the question of whether Langerhans cell histiocytosis is a reactive or a neoplastic process.

摘要

一名有霍奇金淋巴瘤家族史的10岁女孩，出现了2个月的颈部淋巴结病和体重减轻症状。活检显示朗格汉斯细胞组织细胞增多症和霍奇金淋巴瘤同时累及淋巴结。这种关联很罕见，尤其是在儿童中，但并非孤立现象，从而引发了关于朗格汉斯细胞组织细胞增多症是反应性还是肿瘤性过程的问题。