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血液透析患者的实验室检查资料——一家农村三级护理医院的回顾性一年研究

Laboratory Profiles of Patients on Hemodialysis - A Retrospective One Year Study in a Rural Tertiary Care Hospital.

作者信息

Vijayalakshmi Udipi Badikillaya, Rayidi Manasa

机构信息

Associate Professor, Department of Biochemistry, Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation (Dr. PSIMS & RF) Chinnavutapalli, Gannavaram Mandal, Krishna District, Andhra Pradesh, India .

Tutor, Department of Biochemistry, Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation (Dr. PSIMS & RF) Chinnavutapalli, Gannavaram Mandal, Krishna District, Andhra Pradesh, India .

出版信息

J Clin Diagn Res. 2015 Oct;9(10):BC12-5. doi: 10.7860/JCDR/2015/14928.6697. Epub 2015 Oct 1.

Abstract

INTRODUCTION

The global prevalence of chronic kidney disease (CKD) is estimated to be 8-16%. Studies have shown that the increased mortality in patients with CKD is due to anemia that leads to cardiovascular disease (CVD), also known as "Cardio renal anemia syndrome". The present study was undertaken to look into the laboratory profiles of end stage renal disease (ESRD) patients.

AIM

To study the laboratory profiles of End stage renal disease (ESRD) patients coming for hemodialysis.

MATERIALS AND METHODS

The study was a retrospective, cross- sectional study done by collecting data from the medical case records of all patients during a period of one year from January 1(st) 2014 to December 31(st) 2014. Records of a total of 140 patients who underwent hemodialysis during this period were taken. The laboratory profiles that was recorded included haemoglobin, serum sodium, potassium, chloride, fasting glucose, calcium and phosphorus.

RESULTS

The mean age of the subjects was 53.5±14.5 yrs. All the patients had moderate anaemia. There was a significant difference in the mean systolic and diastolic blood pressure, serum creatinine and serum urea values between males and females. The mean serum calcium levels were low.

CONCLUSION

The present study is the first such study in this rural area and shows evidence of a relatively young population with ESRD having moderate anaemia and hypertension. There is evidence of hypocalcaemia and serum phosphorus is on the higher end of the normal range. These findings are usually associated with a higher risk of mortality. With the explosion of diabetes and hypertension in India, chronic kidney disease should be diagnosed and managed as early as possible if not prevented.

摘要

引言

据估计,全球慢性肾脏病(CKD)的患病率为8%-16%。研究表明,CKD患者死亡率增加是由于贫血导致心血管疾病(CVD),也称为“心肾贫血综合征”。本研究旨在探讨终末期肾病(ESRD)患者的实验室检查结果。

目的

研究前来进行血液透析的终末期肾病(ESRD)患者的实验室检查结果。

材料与方法

本研究是一项回顾性横断面研究,通过收集2014年1月1日至2014年12月31日这一年期间所有患者的医疗病例记录中的数据进行。选取了在此期间接受血液透析的总共140例患者的记录。记录的实验室检查结果包括血红蛋白、血清钠、钾、氯、空腹血糖、钙和磷。

结果

受试者的平均年龄为53.5±14.5岁。所有患者均有中度贫血。男性和女性之间的平均收缩压和舒张压、血清肌酐和血清尿素值存在显著差异。平均血清钙水平较低。

结论

本研究是该农村地区的首例此类研究,表明ESRD患者群体相对年轻,存在中度贫血和高血压。有低钙血症的证据,血清磷处于正常范围的较高水平。这些发现通常与较高的死亡风险相关。随着印度糖尿病和高血压的激增,如果无法预防,慢性肾脏病应尽早诊断和管理。

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