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血液透析患者血管通路分析——单中心经验

Analysis of Vascular Access in Haemodialysis Patients - Single Center Experience.

作者信息

Hemachandar R

机构信息

Assistant Professor, Department of Nephrology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University , Puducherry, India .

出版信息

J Clin Diagn Res. 2015 Oct;9(10):OC01-4. doi: 10.7860/JCDR/2015/13342.6611. Epub 2015 Oct 1.

Abstract

BACKGROUND

Vascular access is the key in successful management of chronic haemodialysis (HD) patients. Though native arteriovenous fistula (AVF) is considered the access of choice, many patients in our country initiate haemodialysis through central venous catheter (CVC). There is paucity of data on vascular access in haemodialysis patients from southern India.

AIM

Aim of the present study was to review our experience of vascular access in Haemodialysis patients (both central venous catheters and arteriovenous fistula) and to assess its success rate and common complications.

MATERIALS AND METHODS

This prospective study was conducted between January 2014 and December 2014 in our institute. A total of 50 patients with Chronic Kidney Disease (CKD) underwent vascular access intervention during the above period.

RESULTS

A temporary venous catheter (96%) in the right internal jugular vein was the most common mode of initiation of haemodialysis with 34.48% incidence of catheter related sepsis. Fifty percent of catheters were removed electively with mean duration of catheter survival of 77.23 ± 14.8 days. Wrist AVF (60%) was the most common site of AVF creation followed by arm (30%), mid-forearm (7.5%) and leg (2.5%). Complications include distal oedema (17.5%) and venous hypertension (2.5%). Primary failure occurred in 25% of patients and was more common in diabetic, elderly (>60 years) and in distal fistulas. Elderly patients (>60 years) starting dialysis with a CVC were more likely to be CVC dependent at 90 days.

CONCLUSION

Late presentation and delayed diagnosis of chronic kidney disease (CKD) necessitates dialysis initiation through temporary catheter. Dialysis catheter with its attendant complications further adds to the morbidity, mortality, health care burden and costs. Early nephrology referral and permanent access creation in the pre dialysis stage could avert the unnecessary complications and costs of catheter.

摘要

背景

血管通路是成功管理慢性血液透析(HD)患者的关键。尽管自体动静脉内瘘(AVF)被认为是首选的血管通路,但我国许多患者通过中心静脉导管(CVC)开始进行血液透析。来自印度南部的血液透析患者血管通路的数据较少。

目的

本研究的目的是回顾我们在血液透析患者血管通路(包括中心静脉导管和动静脉内瘘)方面的经验,并评估其成功率和常见并发症。

材料与方法

本前瞻性研究于2014年1月至2014年12月在我们研究所进行。在此期间,共有50例慢性肾脏病(CKD)患者接受了血管通路干预。

结果

右颈内静脉置入临时静脉导管(96%)是最常见的血液透析起始方式,导管相关败血症发生率为34.48%。50%的导管被选择性拔除,导管存活的平均时长为77.23±14.8天。腕部AVF(60%)是最常见的AVF建立部位,其次是手臂(30%)、前臂中部(7.5%)和腿部(2.5%)。并发症包括远端水肿(17.5%)和静脉高压(2.5%)。25%的患者出现原发性失败,在糖尿病患者、老年患者(>60岁)和远端内瘘患者中更为常见。开始使用CVC进行透析的老年患者(>60岁)在90天时更有可能依赖CVC。

结论

慢性肾脏病(CKD)的延迟就诊和诊断延迟使得有必要通过临时导管开始透析。透析导管及其伴随的并发症进一步增加了发病率、死亡率、医疗负担和成本。早期肾病转诊和在透析前阶段建立永久性血管通路可以避免导管带来的不必要并发症和成本。

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