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美国血液透析血管通路的全国实践模式概况

National profile of practice patterns for hemodialysis vascular access in the United States.

作者信息

Reddan Donal, Klassen Preston, Frankenfield Diane L, Szczech Lynda, Schwab Steve, Coladonato Joseph, Rocco Michael, Lowrie Edmund G, Owen William F

机构信息

Duke Institute of Renal Outcomes Research and Health Policy, Duke University Medical Center, Durham, North Carolina 27710, USA.

出版信息

J Am Soc Nephrol. 2002 Aug;13(8):2117-24. doi: 10.1097/01.asn.0000022422.79790.a8.

Abstract

The Centers for Medicare & Medicaid Service's (CMS), national End-Stage Renal Disease (ESRD) Clinical Performance Measures (CPM) Project is a data collection initiative to identify opportunities for improvement of care to adult, Medicare maintenance dialysis beneficiaries. This analysis of 1999 CPM data characterizes the profile of hemodialysis vascular access in the United States and identifies determinants of vascular access type 2 yr after the translation of vascular access clinical practice guideline statements into national CPMs. CPM data were collected during October to December 1999 and stratified by the 18 regional ESRD networks. Univariate and multivariable analyses were conducted to examine associations of access type with demographic, laboratory, and geographic variables. Multivariable logistic regression analyses were performed to identify independent variables associated with access type. A total of 8154 hemodialysis patients were sampled; 17% (n = 1399) were incident. Twenty-eight percent were dialyzed through an autologous arteriovenous fistula (AVF), 49% through a prosthetic graft (AVG), and 23% through a percutaneous catheter. Independent predictors of having a catheter for hemodialysis were female gender, white race, incident to hemodialysis status, and lower hemoglobin and serum albumin. For patients with a fistula or AVG, female gender (odds ration [OR], 2.46 [2.18 to 2.78]) and black race (OR, 1.70 [1.50 to 1.93]) were the strongest predictors of dialysis through an AVG. Other predictors of dialysis through an AVG were older age, increased body mass index (BMI), diabetes mellitus as the cause of ESRD, and lower serum albumin. Even in adjusted analyses, there was significant geographic variability with respect to hemodialysis access type. Despite translation of practice guidelines for hemodialysis vascular access into national CPMs, there is substantial geographic variability and gender and racial disparity in angioaccess allocation in the United States. Quality improvement strategies to improve the prevalence of fistulae should focus on selected regions and include physician education about their practice patterns and potential biases.

摘要

医疗保险和医疗补助服务中心(CMS)的全国终末期肾病(ESRD)临床绩效指标(CPM)项目是一项数据收集计划,旨在确定改善成年医疗保险维持性透析受益人的护理的机会。这项对1999年CPM数据的分析描述了美国血液透析血管通路的概况,并确定了血管通路临床实践指南声明转化为国家CPM两年后血管通路类型的决定因素。CPM数据于1999年10月至12月收集,并按18个地区ESRD网络进行分层。进行单变量和多变量分析以检查通路类型与人口统计学、实验室和地理变量之间的关联。进行多变量逻辑回归分析以确定与通路类型相关的独立变量。总共抽取了8154名血液透析患者;17%(n = 1399)为新发病例。28%通过自体动静脉内瘘(AVF)进行透析,49%通过人工血管移植物(AVG)进行透析,23%通过经皮导管进行透析。进行血液透析使用导管的独立预测因素为女性、白人种族、血液透析新发病例状态以及较低的血红蛋白和血清白蛋白。对于使用内瘘或AVG的患者,女性(优势比[OR],2.46[2.18至2.78])和黑人种族(OR,1.70[1.50至I.93])是通过AVG进行透析的最强预测因素。通过AVG进行透析的其他预测因素为年龄较大、体重指数(BMI)增加、糖尿病作为ESRD的病因以及较低的血清白蛋白。即使在调整分析中,血液透析通路类型在地理上也存在显著差异。尽管血液透析血管通路的实践指南已转化为国家CPM,但在美国血管通路分配方面仍存在显著的地理差异以及性别和种族差异。提高内瘘普及率的质量改进策略应侧重于特定地区,并包括对医生关于其实践模式和潜在偏倚的教育。

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