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女性排尿功能障碍:如何正确处理

Voiding dysfunction in women: How to manage it correctly.

作者信息

Abdel Raheem A, Madersbacher Helmut

机构信息

Department of Urology, Tanta University Hospital, Egypt.

Department of Neurology, Medical University Innsbruck, Austria.

出版信息

Arab J Urol. 2013 Dec;11(4):319-30. doi: 10.1016/j.aju.2013.07.005. Epub 2013 Aug 29.

Abstract

INTRODUCTION

Of women aged >40 years, 6% have voiding dysfunction (VD), but the definition for VD in women with respect to detrusor underactivity (DU) and bladder outlet obstruction (BOO) is not yet clear. In this review we address the current literature to define the diagnosis and treatment of VD more accurately.

METHODS

We used the PubMed database (1975-2012) and searched for original English-language studies using the keywords 'female voiding dysfunction', 'detrusor underactivity', 'acontractile detrusor' and 'bladder outlet obstruction and urinary retention in women'. We sought studies including the prevalence, aetiology, pathogenesis, diagnosis and treatment of female VD.

RESULTS

In all, 20 original studies were identified using the selected search criteria, and another 45 were extracted from the reference lists of the original papers. All studies were selected according to their relevance to the current topic and the most pertinent reports were incorporated into this review.

CONCLUSION

Female VD might be related to DU or/and BOO. Voiding and storage symptoms can coexist, making the diagnosis challenging, with the need for a targeted clinical investigation, and further evaluation by imaging and urodynamics. To date there is no universally accepted precise diagnostic criterion to diagnose and quantify DU and BOO in women. For therapy, a complete cure might not be possible for patients with VD, therefore relieving the symptoms and minimising the long-term complications associated with it should be the goal. Treatment options are numerous and must be applied primarily according to the underlying pathophysiology, but also considering disease-specific considerations and the abilities and needs of the individual patient. The treatment options range from behavioural therapy, intermittent (self-)catheterisation, and electrical neuromodulation and neurostimulation, and up to urinary diversion in rare cases.

摘要

引言

40岁以上女性中,6%存在排尿功能障碍(VD),但女性排尿功能障碍中逼尿肌活动低下(DU)和膀胱出口梗阻(BOO)的定义尚不清楚。在本综述中,我们梳理当前文献以更准确地界定VD的诊断和治疗。

方法

我们使用PubMed数据库(1975 - 2012年),通过关键词“女性排尿功能障碍”“逼尿肌活动低下”“无收缩力逼尿肌”以及“女性膀胱出口梗阻与尿潴留”搜索英文原创研究。我们查找有关女性VD的患病率、病因、发病机制、诊断和治疗的研究。

结果

依据选定的搜索标准,共识别出20项原创研究,另外从原始论文的参考文献列表中提取了45项。所有研究均根据其与当前主题的相关性进行筛选,最相关的报告被纳入本综述。

结论

女性VD可能与DU或/和BOO相关。排尿和储尿症状可能并存,这使得诊断具有挑战性,需要进行有针对性的临床检查,并通过影像学和尿动力学进行进一步评估。迄今为止,尚无普遍接受的精确诊断标准来诊断和量化女性的DU和BOO。对于治疗,VD患者可能无法完全治愈,因此缓解症状并将与之相关的长期并发症降至最低应是目标。治疗选择众多,必须主要根据潜在的病理生理学应用,但也要考虑疾病的具体情况以及个体患者的能力和需求。治疗选择范围从行为疗法、间歇性(自我)导尿、电神经调节和神经刺激,到极少数情况下的尿流改道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/806c/4443013/4e43a61935ef/fx1.jpg

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