Steinert Hans C, Aberle Susanne
1 Interdisziplinäres Schilddrüsenzentrum, Klinik für Nuklearmedizin, Universitätsspital Zürich.
Praxis (Bern 1994). 2015 Nov 11;104(23):1235-43; quiz 1244-5. doi: 10.1024/1661-8157/a002189.
Differentiated thyroid carcinomas represent about 90% of all thyroid tumors and are divided in papillary and follicular carcinomas. Their prognosis is good, however, recurrences are not rare. Their ability to accumulate iodine is used for the radioactive iodine treatment. The aim of the postoperative radioactive iodine ablation therapy is the complete elimination of remnant thyroid cells and sensitive staging (Fig. 1). The recurrence rate decreases after a complete thyroid ablation. Furthermore, thyroglobulin can be used as a sensitive tumor marker. Radioactive iodine treatment by itself describes the therapy of metastases. An exception is the papillary microcarcinoma, which in general is treated by a lobectomy alone.
分化型甲状腺癌约占所有甲状腺肿瘤的90%,分为乳头状癌和滤泡状癌。其预后良好,然而,复发并不罕见。它们摄取碘的能力被用于放射性碘治疗。术后放射性碘消融治疗的目的是彻底清除残余甲状腺细胞并进行敏感分期(图1)。甲状腺完全消融后复发率会降低。此外,甲状腺球蛋白可作为一种敏感的肿瘤标志物。放射性碘治疗本身适用于转移灶的治疗。乳头状微小癌是个例外,一般仅行甲状腺叶切除术治疗。