Schindler Antonio, Pizzorni Nicole, Fantini Marco, Crosetti Erika, Bertolin Andy, Rizzotto Giuseppe, Succo Giovanni
Department of Biomedical and Clinical Sciences "L. Sacco", University of Milan, Milan, Italy.
Department of Otorhinolaryngology, Ospedale San Luigi Gonzaga, University of Turin, Italy.
Head Neck. 2016 Apr;38 Suppl 1:E1427-35. doi: 10.1002/hed.24254. Epub 2015 Nov 11.
The purpose of this study was to compare long-term swallowing, voice results, and quality of life (QOL) after open partial horizontal laryngectomy (OPHL) type IIa and type IIIa.
Twenty-three patients after OPHL type IIa and 18 patients after OPHL type IIIa were involved. Swallowing skills and neoglottis' motility and vibrations were videoendoscopically assessed. Aerodynamic measures, spectrogram analysis, aspiration pneumonia, body weight variations, and voice perceptual assessment were performed. Generic voice-related and swallowing-related QOL were assessed. Data were statistically compared using Mann-Whitney U test or Fisher exact tests, as appropriate.
Significant differences were found only for the residue with solids and for the intelligibility (I) parameter of the overall quality impression and intelligibility, additive and unnecessary noise, speech fluency, and presence of voiced segments scale with patients of the OPHL type IIIa group showing worse performances than the OPHL type IIa group.
Patients who underwent OPHL type IIa and type IIIa show comparable long-term functional outcomes. OPHL type IIIa represents a valid surgical alternative to OPHL type IIa. © 2015 Wiley Periodicals, Inc. Head Neck 38: E1427-E1435, 2016.
本研究旨在比较IIa型和IIIa型开放性部分水平喉切除术（OPHL）后的长期吞咽、嗓音结果及生活质量（QOL）。
纳入23例接受IIa型OPHL的患者和18例接受IIIa型OPHL的患者。通过视频内镜评估吞咽技巧以及新声门的运动和振动情况。进行了空气动力学测量、频谱分析、吸入性肺炎、体重变化及嗓音感知评估。评估了与嗓音和吞咽相关的一般生活质量。数据根据情况使用曼-惠特尼U检验或费舍尔精确检验进行统计学比较。
仅在固体食物残留以及总体质量印象和可懂度的可懂度（I）参数、附加和不必要噪声、言语流畅性以及有声段量表方面发现显著差异，IIIa型OPHL组患者的表现比IIa型OPHL组差。
接受IIa型和IIIa型OPHL的患者显示出相当的长期功能结果。IIIa型OPHL是IIa型OPHL一种有效的手术替代方案。© 2015威利期刊公司。《头颈》38: E1427 - E1435，2016年。
