Butt Usman Ismat, Khan Ahsan, Nawaz Allah, Ayyaz Mahmood, Mansoor Rashid, Malik Awais Amjad, Fatima Tehreem
Department of Surgery, Services Hospital, Lahore, Pakistan.
Department of Anatomy, Services Hospital, Lahore, Pakistan.
J Pak Med Assoc. 2015 Nov;65(11):1228-30.
Gastro-Intestinal Stromal Tumours are rare tumours, constituting less than 1% of gastrointestinal tumours. They are the most common mesenchymal origin tumours of gastro-intestinal tract. Tyrosine kinase c-kit oncogene mutation is found in all cases. These tumours are sensitive to imatinib. They are usually noted incidentally on endoscopy or present with haematemesis after ulceration. We are reporting the laparoscopic resection of GIST in a 67 year old male who had presented with haematemesis. He was found to have a gastric polyp on endoscopy. Endoscopic ultra-soundshowed the tumour to be arising from the submucosa. Histo-pathology showed the tumour to be GIST. Patient is currently undergoing chemotherapy.
胃肠道间质瘤是罕见肿瘤，占胃肠道肿瘤的比例不到1%。它们是胃肠道最常见的间叶源性肿瘤。所有病例均发现酪氨酸激酶c-kit癌基因突变。这些肿瘤对伊马替尼敏感。它们通常在内镜检查时偶然发现，或在溃疡后出现呕血症状。我们报告了一例67岁男性因呕血接受腹腔镜下胃肠道间质瘤切除术的病例。内镜检查发现他有胃息肉。内镜超声显示肿瘤起源于黏膜下层。组织病理学检查显示该肿瘤为胃肠道间质瘤。患者目前正在接受化疗。
