Tripathi R C, Monninger R H, Tripathi B J
Fortschr Ophthalmol. 1989;86(1):67-71.
Acanthamoeba keratitis is a serious complication of contact lens wear. The majority of reports documented in the literature are from the USA. The typical features of this condition are reported and illustrated by personal observations. Clinically, Acanthamoeba keratitis can be misdiagnosed as viral, especially Herpes simplex, fungal, or bacterial keratitis. Culture and microscopic examination of corneal scrapings, biopsy, or of the disc obtained at keratoplasty, and special staining techniques, including indirect immunofluorescence, can provide the definitive diagnosis. We discuss the medical and surgical management of this disease, as well as the risk factors and preventive measures. Knowledge of the factors which are responsible for the low incidence of contact lens-associated Acanthamoeba keratitis in Europe, would be helpful in understanding the epidemiology of this disease.
棘阿米巴角膜炎是隐形眼镜佩戴的一种严重并发症。文献记载的大多数报告来自美国。本文通过个人观察报告并阐述了该病的典型特征。临床上，棘阿米巴角膜炎可能会被误诊为病毒性角膜炎，尤其是单纯疱疹病毒性角膜炎、真菌性角膜炎或细菌性角膜炎。对角膜刮片、活检组织或角膜移植术中获取的植片进行培养和显微镜检查，以及包括间接免疫荧光在内的特殊染色技术，可提供明确诊断。我们讨论了该病的药物和手术治疗方法，以及危险因素和预防措施。了解欧洲与隐形眼镜相关的棘阿米巴角膜炎发病率较低的原因，将有助于理解该病的流行病学。
