Frank Joseph W, Binswanger Ingrid A, Calcaterra Susan L, Brenner Lisa A, Levy Cari
Division of General Internal Medicine, University of Colorado School of Medicine, 12631 East 17th Avenue, Aurora, CO 80045, United States; VA Eastern Colorado Health Care System, 1055 Clermont Street, Denver, CO 80220, United States.
Division of General Internal Medicine, University of Colorado School of Medicine, 12631 East 17th Avenue, Aurora, CO 80045, United States; Institute for Health Research, Kaiser Permanente Colorado, 10065 East Harvard Avenue, Suite 300, Denver, CO 80231, United States.
Drug Alcohol Depend. 2015 Dec 1;157:150-7. doi: 10.1016/j.drugalcdep.2015.10.027. Epub 2015 Oct 29.
There are no population-based studies of emergency department (ED) utilization by individuals using prescription pain medications non-medically. We examined whether non-medical use of prescription pain medications was independently associated with increased ED utilization.
We conducted a retrospective analysis of a nationally representative sample of the non-institutionalized, civilian U.S. population in the National Survey on Drug Use and Health, 2008-2013. We used multivariable logistic regression to examine the association between past year ED utilization and non-medical use of prescription pain medications, defined as use of medications "not prescribed for you or that you took only for the experience or feeling they caused".
An estimated 10.5 million adults annually reported past year non-medical use (NMU) of prescription pain medications, and 39%, or 4.1 million adults annually, also reported one or more past year ED visits. After adjustment for sociodemographic and clinical characteristics, adults with past year NMU of prescription pain medications had increased odds of past year ED utilization (adjusted odds ratio 1.32; 95% confidence interval 1.24-1.41). In secondary analyses, individuals with more frequent NMU had increased odds of ED utilization in unadjusted analyses, but this association was attenuated with adjustment for the source of prescription pain medication (i.e., physician, friend/family, other source).
Non-medical use of prescription pain medications is associated with increased ED utilization. Further work is needed to identify the optimal role of ED settings in providing screening, education, and treatment referral for individuals using prescription pain medications non-medically.
目前尚无基于人群的关于非医疗使用处方止痛药的个体急诊室(ED)就诊情况的研究。我们研究了非医疗使用处方止痛药是否与急诊室就诊增加独立相关。
我们对2008 - 2013年美国国家药物使用和健康调查中具有全国代表性的非机构化平民样本进行了回顾性分析。我们使用多变量逻辑回归来研究过去一年急诊室就诊与非医疗使用处方止痛药之间的关联,非医疗使用处方止痛药定义为使用“未为您开具或您仅为其所带来的体验或感觉而服用的药物”。
估计每年有1050万成年人报告过去一年非医疗使用(NMU)处方止痛药,其中39%,即每年410万成年人,还报告过去一年有一次或多次急诊室就诊。在对社会人口统计学和临床特征进行调整后,过去一年非医疗使用处方止痛药的成年人过去一年急诊室就诊的几率增加(调整后的优势比为1.32;95%置信区间为1.24 - 1.41)。在二次分析中,非医疗使用频率更高的个体在未调整分析中急诊室就诊的几率增加,但在对处方止痛药来源(即医生、朋友/家人、其他来源)进行调整后,这种关联减弱。
非医疗使用处方止痛药与急诊室就诊增加有关。需要进一步开展工作,以确定急诊室在为非医疗使用处方止痛药的个体提供筛查、教育和治疗转诊方面的最佳作用。