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空肠血管发育异常导致反复胃肠道出血,表现为严重贫血和黑便。

Jejunal angiodysplasia causing recurrent gastrointestinal bleeding presenting as severe anaemia and melena.

作者信息

Tiwary Satyendra K, Hakim Md Zeeshan, Kumar Puneet, Khanna Ajay Kumar

机构信息

Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

出版信息

BMJ Case Rep. 2015 Nov 13;2015:bcr2015212798. doi: 10.1136/bcr-2015-212798.

Abstract

Angiodysplasia of the gastrointestinal (GI) tract consists of ectasia of the submucosal vessels of the bowel. The evaluation of such patients needs proctoscopy, colonoscopy, small bowel enema, enteroscopy, capsule enteroscopy and angiography. Capsule enteroscopy has come up as an alternative to GI enteroscopy and colonoscopy in patients with occult GI bleeding; up to 52% cases of small bowel angiodysplasia in patients with occult GI bleed with negative upper GI and colonoscopy have been reported. The use of capsule enteroscopy potentially limits the hazard of radiation exposure from angiography and is less invasive than double balloon endoscopy. The treatment options for angiodysplasias include intra-arterial vasopressin injection, selective gel foam embolisation, endoscopic electrocoagulation and injection of sclerosants, with each of these being technically demanding, and requiring centres with good access to enteroscopy technology and trained gastroenterologists. Operative intervention has been indicated for refractory bleeding or lesions in sites not accessible to endoscopic interventions.

摘要

胃肠道血管发育异常由肠道黏膜下血管扩张组成。对此类患者的评估需要直肠镜检查、结肠镜检查、小肠灌肠、小肠镜检查、胶囊内镜检查和血管造影。在隐匿性胃肠道出血患者中,胶囊内镜检查已成为胃肠道内镜检查和结肠镜检查的替代方法;据报道,在上消化道和结肠镜检查阴性的隐匿性胃肠道出血患者中,高达52%的病例存在小肠血管发育异常。使用胶囊内镜检查可能会减少血管造影带来的辐射暴露风险,并且比双气囊内镜检查侵入性更小。血管发育异常的治疗选择包括动脉内注射血管加压素、选择性明胶海绵栓塞、内镜电凝和注射硬化剂,这些操作技术要求高,需要具备良好小肠镜检查技术的中心和训练有素的胃肠病学家。对于难治性出血或内镜干预无法到达部位的病变,已表明需要进行手术干预。

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