King Stephen Duane, Fitchett George, Murphy Patricia E, Pargament Kenneth I, Martin Paul J, Johnson Rebecca H, Harrison David A, Loggers Elizabeth Trice
Chaplaincy, Seattle Cancer Care Alliance, Seattle, WA, USA.
Department of Religion, Health & Human Values, Rush University Medical Center, Chicago, IL, USA.
Psychooncology. 2017 Feb;26(2):270-277. doi: 10.1002/pon.4029. Epub 2015 Nov 15.
This study describes the prevalence of religious or spiritual (R/S) struggle in long-term survivors after hematopoietic cell transplantation (HCT), demographic and medical correlates of R/S struggle, and its associations with depression and quality of life.
Data were collected in conjunction with an annual survey of adult (age ≥18 years) survivors of HCT. Study measures included R/S struggle (negative religious coping, NRC, from Brief RCOPE), measures of quality of life (subscales from 36-item Short Form Health Survey and McGill), and the Patient Health Questionnaire 8. R/S struggle was defined as any non-zero response on the NRC. Factors associated with R/S struggle were identified using multi-variable logistic regression models.
The study analyzed data from 1449 respondents who ranged from 6 months to 40 years after HCT. Twenty-seven percent had some R/S struggle. In a multi-variable logistic regression model, R/S struggle was associated with greater depression and poorer quality of life. R/S struggle was also associated with younger age, non-White race, and self-identification as either religious but not spiritual or spiritual but not religious. R/S struggle was not associated with any medical variables, including time since transplant.
Religious or spiritual struggle is common among HCT survivors, even many years after HCT. Survivors should be screened and, as indicated, referred to a professional with expertise in R/S struggle. Further study is needed to determine causal relationships, longitudinal trajectory, impact of struggle intensity, and effects of R/S struggle on health, mood, and social roles for HCT survivors. Copyright © 2015 John Wiley & Sons, Ltd.
本研究描述了造血细胞移植（HCT）后长期存活者中宗教或精神（R/S）挣扎的发生率、R/S挣扎的人口统计学和医学相关因素，以及它与抑郁和生活质量的关联。
数据收集是结合对成年（年龄≥18岁）HCT存活者的年度调查进行的。研究测量指标包括R/S挣扎（来自简明宗教应对量表的消极宗教应对，NRC）、生活质量测量指标（36项简短健康调查问卷和麦吉尔量表的子量表）以及患者健康问卷8。R/S挣扎被定义为NRC上的任何非零反应。使用多变量逻辑回归模型确定与R/S挣扎相关的因素。
该研究分析了1449名受访者的数据，这些受访者处于HCT后6个月至40年之间。27%的人有某种R/S挣扎。在多变量逻辑回归模型中，R/S挣扎与更严重的抑郁和更差的生活质量相关。R/S挣扎还与较年轻的年龄、非白人种族以及自我认同为宗教但非精神或精神但非宗教有关。R/S挣扎与任何医学变量均无关联，包括移植后的时间。
宗教或精神挣扎在HCT存活者中很常见，即使在HCT多年后也是如此。应对存活者进行筛查，并在必要时转介给具有R/S挣扎专业知识的专业人员。需要进一步研究以确定因果关系、纵向轨迹、挣扎强度的影响以及R/S挣扎对HCT存活者的健康、情绪和社会角色的影响。版权所有©2015约翰威立父子有限公司。
