Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Republic of Korea.
Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Republic of Korea.
Biosens Bioelectron. 2016 Mar 15;77:1144-52. doi: 10.1016/j.bios.2015.11.012. Epub 2015 Nov 5.
This paper reports that the high electrocatalytic activity of RuO2 nanowires grown on electrospun TiO2 nanofibers for the oxidation of l-ascorbic acid (AA); and the application of these materials for direct selective sensing of AA in complex samples. Compared to bare glassy carbon (GC) electrode, RuO2 nanowires on TiO2 nanofibers-loaded GC electrode facilitates the oxidation of AA most drastically among the tested species: AA, 4-acetamidophenol (AP), dopamine (DA), uric acid (UA), and glucose. The amperometric response of RuO2 nanowires on TiO2 nanofibers at the applied potential of 0.018 V (vs. SCE) exhibits high sensitivity (268.2 ± 3.7 μAmM(-1)cm(-2), n=5), low detection limit (<1.8 μM), great linearity, reasonable stability, and exclusive selectivity over AP, DA, glucose and UA at their physiological levels. In differential pulse voltammetry, it is verified that the potential resolution of RuO2 nanowires on TiO2 nanofibers is able to differentiate AA, DA, UA, and AP one from the others. In addition, as prepared RuO2 nanowires on TiO2 nanofibers are successfully applied for direct and selective AA measurements in commercial vitamin samples and for the real-time direct analysis of AA generated from living rat liver tissue in vitro.
本文报道了在静电纺丝 TiO2 纳米纤维上生长的 RuO2 纳米线对 l-抗坏血酸（AA）氧化具有高电催化活性；并将这些材料应用于复杂样品中 AA 的直接选择性传感。与裸玻碳（GC）电极相比，负载 TiO2 纳米纤维的 RuO2 纳米线/GC 电极在测试的物种中最剧烈地促进 AA 的氧化：AA、4-乙酰氨基酚（AP）、多巴胺（DA）、尿酸（UA）和葡萄糖。在 0.018 V（相对于 SCE）的施加电位下，RuO2 纳米线在 TiO2 纳米纤维上的安培响应表现出高灵敏度（268.2 ± 3.7 μAmM-1cm-2，n=5）、低检测限（<1.8 μM）、良好的线性、合理的稳定性以及对 AP、DA、葡萄糖和 UA 在生理水平下的选择性。在差分脉冲伏安法中，验证了 RuO2 纳米线在 TiO2 纳米纤维上的电位分辨率能够区分 AA、DA、UA 和 AP。此外，所制备的 RuO2 纳米线在 TiO2 纳米纤维上成功应用于商业维生素样品中 AA 的直接和选择性测量，以及用于体外实时分析来自活鼠肝组织的 AA。
