Denissen H W, Kalk W, Veldhuis A A, van den Hooff A
University of Nÿmegen, Dental School, The Netherlands.
J Prosthet Dent. 1989 Jun;61(6):706-12. doi: 10.1016/s0022-3913(89)80047-2.
An 11-year clinical research study was conducted with both unloaded bulk hydroxyapatite implants and loaded hydroxyapatite-coated titanium implants. A total of 102 submerged bulk hydroxyapatite implants were placed after extraction of teeth to maintain the volume of the residual alveolar ridge by their physical presence. All 21 implants under fixed partial dentures and 51 of 81 implants under lower complete dentures remained submucosal. A total of 71 hydroxyapatite-coated titanium implants were connected with permucosal superstructures by use of a two-stage method. Modifications in design and in implantation technique were required. This long-term research indicates that cylindrical hydroxyapatite implants are reliable devices as natural tooth root substitutes that bond directly to bone instead of simply being osseointegrated.
一项为期11年的临床研究对无负载的块状羟基磷灰石植入物和负载的羟基磷灰石涂层钛植入物进行了研究。在拔牙后共植入102颗埋入式块状羟基磷灰石植入物，通过其物理存在来维持残余牙槽嵴的体积。固定局部义齿下的所有21颗植入物以及下全口义齿下81颗植入物中的51颗仍位于黏膜下。共71颗羟基磷灰石涂层钛植入物采用两阶段法与穿黏膜上部结构相连。需要对设计和植入技术进行改进。这项长期研究表明，圆柱形羟基磷灰石植入物作为天然牙根替代品是可靠的装置，它直接与骨结合，而不仅仅是骨整合。
