Wang Yihan, Wang JianChao, Jiang Chong, Peng Qian, Wu Mingpeng, Ma Xuelei
State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, China.
Hell J Nucl Med. 2015 Sep-Dec;18(3):261-3. doi: 10.1967/s002449910309. Epub 2015 Nov 18.
Neurolymphomatosis (NL) is a rare neurological manifestation of lymphoma. Clinical symptoms of NL differ greatly according to the sites involved and diagnosis with conventional imaging techniques may sometimes be difficult. We herein describe the case of a 58 years old man presenting as radiculopathy with a history of non-Hodgkin's lymphoma (NHL). Computed tomography (CT) was unrevealing and magnetic resonance imaging (MRI) was contraindicated. Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) was performed and revealed multiple hypermetabolic lesions along the nerve roots, which corresponded to the patient's neurological symptoms. A differential diagnosis of patients with lymphomatous involvement of spinal nerve roots has been presented.
Our case suggests that ¹⁸F-FDG PET/CT successfully detected the infiltration of spinal nerve roots of NL due to lymphoma.
神经淋巴瘤（NL）是淋巴瘤一种罕见的神经表现。NL的临床症状因受累部位不同而有很大差异，有时用传统成像技术进行诊断可能会有困难。我们在此描述一例58岁男性患者，以神经根病为表现，有非霍奇金淋巴瘤（NHL）病史。计算机断层扫描（CT）未发现异常，磁共振成像（MRI）因禁忌证未进行。进行了氟-18氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（¹⁸F-FDG PET/CT），发现沿神经根有多个高代谢病变，与患者的神经症状相符。本文还对淋巴瘤累及脊神经根的患者进行了鉴别诊断。
我们的病例表明¹⁸F-FDG PET/CT成功检测到了淋巴瘤所致NL的脊神经根浸润。
