Peng Yi, Shu Chang, Fu Zhou, Li Qu-Bei, Liu Zheng, Yan Li
Deparment of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2015 Nov;17(11):1193-9.
To investigate the distribution of pathogens of children with community acquired pneumonia (CAP) from the Chongqing area.
Nasopharyngeal specimens and blood specimens of 1 613 children with CAP were collected between January 2014 and December 2014 for bacterial culture and detection of 7 respiratory viruses and antibodies against Mycoplasma pneumoniae (MP).
The overall positive rate of bacteria was 50.22% (810 cases). Hemophilus parainfluenzae (40.8%), Streptococcus pneumonia (29.7%) and Moraxelle catarrhalis (7.3%) were the predominant ones. Among the viruses, the top detected virus was respiratory syncytial virus (RSV, 58.3%), followed by parainfluenza virus type3 (17.4%) and adenovirus (14.3%). A total of 481 cases (29.82%) were MP-positive. The co-infection rate was 32.18% (519 cases), and the mixed infections of bacteria and viruses were common (47.4%).
RSV and Hemophilus parainfluenzae are the major pathogens of CAP in children from the Chongqing area. MP is also an important pathogen. The co-infection of bacteria and viruses is prevalent.
调查重庆地区社区获得性肺炎（CAP）患儿的病原体分布情况。
收集2014年1月至2014年12月期间1613例CAP患儿的鼻咽标本和血液标本，进行细菌培养以及7种呼吸道病毒和肺炎支原体（MP）抗体检测。
细菌总体阳性率为50.22%（810例）。副流感嗜血杆菌（40.8%）、肺炎链球菌（29.7%）和卡他莫拉菌（7.3%）为主要致病菌。在病毒中，检测到的最常见病毒是呼吸道合胞病毒（RSV，58.3%），其次是3型副流感病毒（17.4%）和腺病毒（14.3%）。共有481例（29.82%）MP检测呈阳性。合并感染率为32.18%（519例），细菌和病毒混合感染较为常见（47.4%）。
RSV和副流感嗜血杆菌是重庆地区CAP患儿的主要病原体。MP也是一种重要病原体。细菌和病毒合并感染很普遍。
