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[与法尔氏综合征相关的精神病:一例报告]

[Psychosis Associated With Fahr's Syndrome: A Case Report].

作者信息

Cassiani-Miranda Carlos Arturo, Herazo-Bustos Mariana, Cabrera-González Armando, Cadena-Ramos Ivan, Barrios-Ayola Francisco

机构信息

Grupo de Investigación en Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Cartagena, Cartagena, Colombia.

Grupo de Investigación en Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Cartagena, Cartagena, Colombia.

出版信息

Rev Colomb Psiquiatr. 2015 Oct-Dec;44(4):256-61. doi: 10.1016/j.rcp.2015.03.006. Epub 2015 May 8.

Abstract

INTRODUCTION

Fahr syndrome (SF) is a rare neurological disorder, characterized by abnormal deposition of calcium in brain areas that control movement.

OBJECTIVE

The case is presented of a 41-year-old female with a convulsive syndrome, psychotic disorder, neurocognitive disorde,r and intellectual disability associated with bilateral brain calcifications and altered calcium/phosphorus metabolism in the context of hypoparathyroidism.

METHOD

Case report.

RESULTS

The calcifications found in the patient could be the cause of psychotic symptoms and cognitive impairment. Diagnostic imaging, laboratory tests, psychiatric and neuropsychological assessments are presented. The clinical presentation of this case is compared with similar ones reported in the literature. Therapeutic approaches and clinical outcomes are described.

CONCLUSIONS

Fahr's syndrome should be suspected in patients with neuropsychiatric disorders and seizures. Neuroimaging studies, and the determining of phosphorus and calcium metabolism and parathyroid hormone levels are important in this type of patient.

摘要

引言

法尔综合征(SF)是一种罕见的神经系统疾病,其特征是在控制运动的脑区出现钙异常沉积。

目的

报告一例41岁女性病例,该患者患有惊厥综合征、精神障碍、神经认知障碍和智力残疾,伴有双侧脑钙化以及甲状旁腺功能减退情况下的钙/磷代谢改变。

方法

病例报告。

结果

患者发现的钙化可能是精神症状和认知障碍的原因。展示了诊断成像、实验室检查、精神科和神经心理学评估。将该病例的临床表现与文献中报道的类似病例进行了比较。描述了治疗方法和临床结果。

结论

患有神经精神障碍和癫痫发作的患者应怀疑患有法尔综合征。神经影像学研究以及磷、钙代谢和甲状旁腺激素水平的测定对这类患者很重要。

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