Lee Yoo Jin, Park Sihyung, Kim Yang Wook, Park Kang Min, Kim Il Hwan, Park Jin Han, Park Bong Soo
Department of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea.
Department of Neurology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea.
Am J Case Rep. 2018 Dec 1;19:1430-1433. doi: 10.12659/AJCR.913382.
BACKGROUND Idiopathic basal ganglia calcification, also known as Fahr's disease or Fahr's syndrome, is a rare neurological disorder characterized by abnormal calcified deposits in the basal ganglia. Here, we report a case of Fahr's syndrome with calcification of the basal ganglia due to hypoparathyroidism in a patient with seizures. CASE REPORT A 52-year-old male patient visited our clinic with seizures. Brain computed tomography (CT) showed bilateral symmetrical calcifications in cerebellar white matter, the corpus striatum, the posterior thalami, and the centrum semiovale of both cerebral hemispheres. He had symptoms of hypocalcemia and low parathyroid hormone levels. The patient was diagnosed with Fahr's syndrome due to primary hypoparathyroidism. He underwent calcium supplementation and calcifediol treatment. His symptoms improved, and he was discharged from the hospital. CONCLUSIONS In patients with hypocalcemia accompanied by parathyroid dysfunction, neurological examination and CT should be performed to confirm abnormal intracranial calcification.
特发性基底节钙化，也称为法尔病或法尔综合征，是一种罕见的神经系统疾病，其特征是基底节出现异常钙化沉积。在此，我们报告一例因甲状旁腺功能减退导致基底节钙化的法尔综合征患者，该患者伴有癫痫发作。病例报告：一名52岁男性患者因癫痫发作前来我院就诊。脑部计算机断层扫描（CT）显示双侧小脑白质、纹状体、丘脑后部以及双侧大脑半球半卵圆中心有对称性钙化。他有低钙血症症状且甲状旁腺激素水平较低。该患者被诊断为原发性甲状旁腺功能减退所致的法尔综合征。他接受了补钙和骨化二醇治疗。症状改善后，他出院了。结论：对于伴有甲状旁腺功能障碍的低钙血症患者，应进行神经系统检查和CT检查以确认颅内异常钙化。
