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粗颗粒物对台湾高雄市这一热带城市每日死亡率的短期影响。

Short-Term Effect of Coarse Particles on Daily Mortality Rate in A Tropical City, Kaohsiung, Taiwan.

作者信息

Tsai Shang-Shyue, Weng Yi-Hao, Chiu Ya-Wen, Yang Chun-Yuh

机构信息

a Department of Healthcare Administration , I-Shou University , Kaohsiung , Taiwan.

b Division of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital , Chang Gung University College of Medicine , Taipei , Taiwan.

出版信息

J Toxicol Environ Health A. 2015;78(23-24):1409-20. doi: 10.1080/15287394.2015.1093674. Epub 2015 Nov 18.

Abstract

Many studies examined the short-term effects of air pollution on frequency of daily mortality over the past two decades. However, information on the relationship between exposure to levels of coarse particles (PM(2.5-10)) and daily mortality rate is relatively sparse due to limited availability of monitoring data and findings are inconsistent. This study was undertaken to determine whether an association exists between PM(2.5-10) levels and rate of daily mortality in Kaohsiung, Taiwan, a large industrial city with a tropical climate. Daily mortality rate, air pollution parameters, and weather data for Kaohsiung were obtained for the period 2006-2008. The relative risk (RR) of daily mortality occurrence was estimated using a time-stratified case-crossover approach, controlling for (1) weather variables, (2) day of the week, (3) seasonality, and (4) long-term time trends. For the single-pollutant model without adjustment for other pollutants, PM(2.5-10) exposure levels showed significant correlation with total mortality rate both on warm and cool days, with an interquartile range increase associated with a 14% (95% CI = 5-23%) and 12% (95% CI = 5-20%) rise in number of total deaths, respectively. In two-pollutant models, PM(2.5-10) exerted significant influence on total mortality frequency after inclusion of sulfur dioxide (SO(2)) on warm days. On cool days, PM(2.5-10) induced significant elevation in total mortality rate when SO(2) or ozone (O(3)) was added in the regression model. There was no apparent indication of an association between PM(2.5-10) exposure and deaths attributed to respiratory and circulatory diseases. This study provided evidence of correlation between short-term exposure to PM(2.5-10) and increased risk of death for all causes.

摘要

在过去二十年里,许多研究探讨了空气污染对每日死亡率的短期影响。然而,由于监测数据有限,关于接触粗颗粒物(PM(2.5 - 10))水平与每日死亡率之间关系的信息相对较少,且研究结果并不一致。本研究旨在确定台湾高雄市(一个拥有热带气候的大型工业城市)的PM(2.5 - 10)水平与每日死亡率之间是否存在关联。我们获取了高雄市2006 - 2008年期间的每日死亡率、空气污染参数和气象数据。使用时间分层病例交叉法估计每日死亡发生的相对风险(RR),同时控制(1)气象变量、(2)星期几、(3)季节性以及(4)长期时间趋势。对于未对其他污染物进行调整的单污染物模型,在温暖和凉爽的日子里,PM(2.5 - 10)暴露水平与总死亡率均呈现显著相关性,四分位间距增加分别与总死亡人数增加14%(95%置信区间 = 5 - 23%)和12%(95%置信区间 = 5 - 20%)相关。在双污染物模型中,在温暖的日子里纳入二氧化硫(SO(2))后,PM(2.5 - 10)对总死亡频率有显著影响。在凉爽的日子里,当回归模型中加入SO(2)或臭氧(O(3))时,PM(2.5 - 10)会导致总死亡率显著升高。没有明显迹象表明PM(2.5 - 10)暴露与呼吸道和循环系统疾病导致的死亡之间存在关联。本研究提供了短期接触PM(2.5 - 10)与全因死亡风险增加之间存在相关性的证据。

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