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1
ATM Kinase Is Required for Telomere Elongation in Mouse and Human Cells.
Cell Rep. 2015 Nov 24;13(8):1623-32. doi: 10.1016/j.celrep.2015.10.035. Epub 2015 Nov 12.
2
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres.
Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2249-51. doi: 10.1073/pnas.0511143103. Epub 2006 Feb 7.
3
ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres.
Cell Rep. 2015 Nov 24;13(8):1633-46. doi: 10.1016/j.celrep.2015.10.041. Epub 2015 Nov 12.
4
53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition.
PLoS One. 2014 Sep 29;9(9):e108731. doi: 10.1371/journal.pone.0108731. eCollection 2014.
6
BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped telomeres.
EMBO J. 2015 Feb 3;34(3):410-24. doi: 10.15252/embj.201488947. Epub 2015 Jan 12.
7
Altering telomere structure allows telomerase to act in yeast lacking ATM kinases.
Curr Biol. 2001 Aug 21;11(16):1240-50. doi: 10.1016/s0960-9822(01)00391-8.
9
GSE4 peptide suppresses oxidative and telomere deficiencies in ataxia telangiectasia patient cells.
Cell Death Differ. 2019 Oct;26(10):1998-2014. doi: 10.1038/s41418-018-0272-7. Epub 2019 Jan 22.
10
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
Nature. 2007 Aug 30;448(7157):1068-71. doi: 10.1038/nature06065. Epub 2007 Aug 8.

引用本文的文献

2
ATM-dependent DNA damage response constrains cell growth and drives clonal hematopoiesis in telomere biology disorders.
J Clin Invest. 2025 Apr 3;135(8). doi: 10.1172/JCI181659. eCollection 2025 Apr 15.
3
Active telomere elongation by a subclass of cancer-associated POT1 mutations.
Genes Dev. 2025 Apr 1;39(7-8):445-462. doi: 10.1101/gad.352492.124.
4
Telomere maintenance and the DNA damage response: a paradoxical alliance.
Front Cell Dev Biol. 2024 Oct 17;12:1472906. doi: 10.3389/fcell.2024.1472906. eCollection 2024.
6
A Mesenchymal stem cell Aging Framework, from Mechanisms to Strategies.
Stem Cell Rev Rep. 2024 Aug;20(6):1420-1440. doi: 10.1007/s12015-024-10732-4. Epub 2024 May 10.
7
Telomeres: Dysfunction, Maintenance, Aging and Cancer.
Aging Dis. 2023 Nov 29;15(6):2595-2631. doi: 10.14336/AD.2023.1128.
8
Fyn-mediated phosphorylation of Menin disrupts telomere maintenance in stem cells.
bioRxiv. 2024 Mar 19:2023.10.04.560876. doi: 10.1101/2023.10.04.560876.
9
Pot1b -/- tumors activate G-quadruplex-induced DNA damage to promote telomere hyper-elongation.
Nucleic Acids Res. 2023 Sep 22;51(17):9227-9247. doi: 10.1093/nar/gkad648.
10
Close Ties between the Nuclear Envelope and Mammalian Telomeres: Give Me Shelter.
Genes (Basel). 2023 Mar 23;14(4):775. doi: 10.3390/genes14040775.

本文引用的文献

2
Mechanisms of ATM Activation.
Annu Rev Biochem. 2015;84:711-38. doi: 10.1146/annurev-biochem-060614-034335. Epub 2015 Jan 12.
4
The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.
Nature. 2012 Dec 13;492(7428):285-9. doi: 10.1038/nature11648. Epub 2012 Oct 24.
5
Sequencing the unsequenceable: expanded CGG-repeat alleles of the fragile X gene.
Genome Res. 2013 Jan;23(1):121-8. doi: 10.1101/gr.141705.112. Epub 2012 Oct 11.
6
The telomere syndromes.
Nat Rev Genet. 2012 Oct;13(10):693-704. doi: 10.1038/nrg3246. Epub 2012 Sep 11.
7
Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice.
J Cell Biol. 2012 Aug 6;198(3):305-13. doi: 10.1083/jcb.201204098.
8
Loss of ATM kinase activity leads to embryonic lethality in mice.
J Cell Biol. 2012 Aug 6;198(3):295-304. doi: 10.1083/jcb.201204035.
9
10
Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors.
Nat Biotechnol. 2012 Feb 19;30(3):283-8. doi: 10.1038/nbt.2121.

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