Engelhardt R P
Laboratoire d'Histologie-Embryologie et Biologie de la Reproduction, Faculté de Médecine, Lille.
Ann Endocrinol (Paris). 1989;50(1):64-72.
A review is presented on the occurrence of opioid systems within mammalian testes at different stages of sexual development. Identification of the messenger ribonucleic acid sequences (mRNA) related to the three opioid precursor families and as well as characterization and localization of their main derivates may account for the importance of such systems within reproductive tissues. These data are supported by experimental in vivo and in vitro studies giving evidence that opioid peptides are produced locally and may exert paracrine and/or autocrine effects within the testes.
本文综述了在哺乳动物性发育不同阶段睾丸中阿片系统的存在情况。对与三个阿片前体家族相关的信使核糖核酸序列（mRNA）的鉴定，以及对其主要衍生物的表征和定位，可能解释了这些系统在生殖组织中的重要性。体内和体外实验研究支持了这些数据，这些研究表明阿片肽在局部产生，并可能在睾丸内发挥旁分泌和/或自分泌作用。
