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持续性非卧床腹膜透析的代谢效应

Metabolic effects of continuous ambulatory peritoneal dialysis.

作者信息

Morrison G

机构信息

Department of Medicine, University of Pennsylvania Medical School, Philadelphia 19104.

出版信息

Annu Rev Med. 1989;40:163-72. doi: 10.1146/annurev.me.40.020189.001115.

Abstract

Chronic ambulatory peritoneal dialysis is associated with a number of metabolic abnormalities. These include lipid abnormalities, most commonly hypertriglyceridemia, increased VLDL and decreased HDL-cholesterol levels; carbohydrate abnormalities, a result of the absorption of large quantities of glucose; protein losses, consisting of albumin and amino acid losses; and a propensity to obesity. The pathogenesis and possible consequences of these abnormalities are discussed.

摘要

慢性非卧床腹膜透析与多种代谢异常有关。这些异常包括脂质异常,最常见的是高甘油三酯血症、极低密度脂蛋白增加和高密度脂蛋白胆固醇水平降低;碳水化合物异常,这是大量葡萄糖吸收的结果;蛋白质丢失,包括白蛋白和氨基酸丢失;以及肥胖倾向。本文讨论了这些异常的发病机制和可能的后果。

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