加拿大多伦多难民中水痘易感性的风险因素。

Risk Factors for Varicella Susceptibility Among Refugees to Toronto, Canada.

作者信息

Cadieux Geneviève, Redditt Vanessa, Graziano Daniela, Rashid Meb

机构信息

Dalla Lana School of Public Health, University of Toronto, 155 College Street, 6th floor, Toronto, ON, M5T 3M7, Canada.

Department of Family and Community Medicine, University of Toronto, Toronto, ON, Canada.

出版信息

J Immigr Minor Health. 2017 Feb;19(1):6-14. doi: 10.1007/s10903-015-0313-y.

DOI:10.1007/s10903-015-0313-y

PMID:26590922

Abstract

Several outbreaks of varicella have occurred among refugees. We aimed to estimate the prevalence of varicella susceptibility among refugees, and identify risk factors for varicella susceptibility. All refugees rostered at Crossroads Clinic in Toronto, Canada in 2011-2014 were included in our study. Varicella serology was assessed at the initial visit. Refugees' age, sex, education, time since arrival, and climate and population density of birth country were abstracted from the chart. Multivariate logistic regression was used to identify risk factors for varicella susceptibility. 1063 refugees were rostered at Crossroads Clinic during the study; 7.9 % (95 % CI 6.1, 9.7) were susceptible to varicella. Tropical climate (OR 3.20, 95 % CI 1.53, 6.69) and younger age (OR 0.92, 95 % CI 0.88-0.96) were associated with increased varicella susceptibility. These risk factors for varicella susceptibility should be taken into account to maximize the cost-effectiveness of varicella prevention strategies among refugees.

摘要

难民群体中已发生多起水痘疫情。我们旨在估算难民中水痘易感性的患病率，并确定水痘易感性的风险因素。2011年至2014年在加拿大多伦多十字路口诊所登记在册的所有难民均纳入我们的研究。在初次就诊时评估水痘血清学。从病历中提取难民的年龄、性别、教育程度、抵达时间以及出生国的气候和人口密度。采用多因素逻辑回归分析确定水痘易感性的风险因素。研究期间，十字路口诊所登记在册1063名难民；7.9%（95%置信区间6.1，9.7）对水痘易感。热带气候（比值比3.20，95%置信区间1.53，6.69）和年龄较小（比值比0.92，95%置信区间0.88 - 0.96）与水痘易感性增加相关。在难民中，为使水痘预防策略的成本效益最大化，应考虑这些水痘易感性的风险因素。