Department of Population Health Sciences, University of Wisconsin, Madison, Wisconsin.
University of Wisconsin Population Health Institute, Madison, Wisconsin.
Am J Prev Med. 2015 Dec;49(6):961-9. doi: 10.1016/j.amepre.2015.07.016.
Although many researchers agree that multiple determinants impact health, there is no consensus regarding the magnitude of the relative contributions of individual health factors to health outcomes. This study presents a method to empirically estimate the relative contributions of health behaviors, clinical care, social and economic factors, and the physical environment to health outcomes using nationally representative county-level data and statistical approaches that account for potential sources of bias. The analyses for this study were conducted in 2014. Data were from the 2010-2013 County Health Rankings & Roadmaps. Data covered 2,996 of 3,141 U.S. counties. Ordinary least squares modeling was used as a baseline model. Multilevel latent growth curve modeling was used to estimate the relative contributions of health factors to health outcomes while accounting for measurement errors and state-specific characteristics. Almost half of the variance of health outcomes was due to state-level variation rather than county-level variation. When adjusted for measurement errors and state-level variation using multilevel latent growth curve modeling, the relative contribution of clinical care decreased and that of social and economic factors increased compared with the baseline model. This study presents how potential sources of bias affected the estimates of the relative contributions of a set of modifiable health factors to health outcomes at the county level. Further verification of these approaches with other data sources could lead to a better understanding of the impact of specific health determinants to health outcomes, and will provide useful information on policy interventions.
虽然许多研究人员认为多种决定因素会影响健康,但对于个体健康因素对健康结果的相对贡献大小,尚未达成共识。本研究提出了一种使用具有代表性的县级数据和能够纠正潜在偏差的统计方法,实证估计健康行为、临床护理、社会经济因素和物理环境对健康结果的相对贡献的方法。本研究的分析于 2014 年进行。数据来自于 2010-2013 年县健康排名和路线图。数据涵盖了美国 3141 个县中的 2996 个县。普通最小二乘法模型被用作基线模型。多层次潜在增长曲线模型用于估计健康因素对健康结果的相对贡献,同时考虑测量误差和州特定特征。健康结果的近一半方差归因于州级差异,而不是县级差异。使用多层次潜在增长曲线模型对测量误差和州级差异进行调整后,与基线模型相比,临床护理的相对贡献降低,社会经济因素的相对贡献增加。本研究介绍了潜在偏差源如何影响可改变的一组健康因素对县级健康结果的相对贡献的估计。使用其他数据源对这些方法进行进一步验证,可以更好地了解特定健康决定因素对健康结果的影响,并为政策干预提供有用的信息。