Wilk Szymon, Kezadri-Hamiaz Mounira, Rosu Daniela, Kuziemsky Craig, Michalowski Wojtek, Amyot Daniel, Carrier Marc
Poznan University of Technology, Poznan, Poland.
University of Ottawa, Ottawa, ON, Canada.
J Med Syst. 2016 Feb;40(2):42. doi: 10.1007/s10916-015-0375-3. Epub 2015 Nov 21.
In healthcare organizations, clinical workflows are executed by interdisciplinary healthcare teams (IHTs) that operate in ways that are difficult to manage. Responding to a need to support such teams, we designed and developed the MET4 multi-agent system that allows IHTs to manage patients according to presentation-specific clinical workflows. In this paper, we describe a significant extension of the MET4 system that allows for supporting rich team dynamics (understood as team formation, management and task-practitioner allocation), including selection and maintenance of the most responsible physician and more complex rules of selecting practitioners for the workflow tasks. In order to develop this extension, we introduced three semantic components: (1) a revised ontology describing concepts and relations pertinent to IHTs, workflows, and managed patients, (2) a set of behavioral rules describing the team dynamics, and (3) an instance base that stores facts corresponding to instances of concepts from the ontology and to relations between these instances. The semantic components are represented in first-order logic and they can be automatically processed using theorem proving and model finding techniques. We employ these techniques to find models that correspond to specific decisions controlling the dynamics of IHT. In the paper, we present the design of extended MET4 with a special focus on the new semantic components. We then describe its proof-of-concept implementation using the WADE multi-agent platform and the Z3 solver (theorem prover/model finder). We illustrate the main ideas discussed in the paper with a clinical scenario of an IHT managing a patient with chronic kidney disease.
在医疗保健机构中,临床工作流程由跨学科医疗团队(IHTs)执行,这些团队的运作方式难以管理。为了满足支持此类团队的需求,我们设计并开发了MET4多智能体系统,该系统允许IHTs根据特定临床表现的临床工作流程来管理患者。在本文中,我们描述了MET4系统的一次重大扩展,该扩展允许支持丰富的团队动态(理解为团队组建、管理和任务 - 从业者分配),包括选择和维护最负责的医生以及为工作流程任务选择从业者的更复杂规则。为了开发此扩展,我们引入了三个语义组件:(1)一个修订的本体,描述与IHTs、工作流程和管理的患者相关的概念和关系;(2)一组描述团队动态的行为规则;(3)一个实例库,存储与本体中的概念实例以及这些实例之间的关系相对应的事实。这些语义组件用一阶逻辑表示,并且可以使用定理证明和模型查找技术自动处理。我们使用这些技术来找到与控制IHT动态的特定决策相对应的模型。在本文中,我们展示了扩展后的MET4的设计,特别关注新的语义组件。然后,我们描述了使用WADE多智能体平台和Z3求解器(定理证明器/模型查找器)对其进行的概念验证实现。我们用一个IHT管理慢性肾病患者的临床场景来说明本文讨论的主要思想。